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Journal of Medicinal Chemistry|July 11, 2006
Novel selective inhibitors of neutral endopeptidase for the treatment of female sexual arousal disorder. Synthesis and activity of functionalized glutaramidesDavid C Pryde, Graham N Maw, Simon Planken, et al.Journal for Immunotherapy of Cancer|June 23, 2026
C92, a proton channel-blocking allosteric STING agonist generates robust antitumor activityMonali Banerjee, Sandip Kumar Middya, Ritesh Shrivastava, et al.Bioorganic & Medicinal Chemistry Letters|September 3, 2011
Discovery of a highly potent series of TLR7 agonistsPeter Jones, David C Pryde, Thien-Duc Tran, et al.Bioorganic & Medicinal Chemistry Letters|January 27, 2009
The design and discovery of novel amide CCR5 antagonistsDavid C Pryde, Martin Corless, David R Fenwick, et al.Angewandte Chemie (International Ed. in English)|May 14, 2014
A series of potent CREBBP bromodomain ligands reveals an induced-fit pocket stabilized by a cation-π interactionTimothy P C Rooney, Panagis Filippakopoulos, Oleg Fedorov, et al.Chemmedchem|April 15, 2014
The discovery of potent nonstructural protein 5A (NS5A) inhibitors with a unique resistance profile-Part 1Thien Duc Tran, Florian Wakenhut, Chris Pickford, et al.Plos One|October 8, 2013
Selection of a novel anti-nicotine vaccine: influence of antigen design on antibody function in miceDavid C Pryde, Lyn H Jones, David P Gervais, et al.Journal of Medicinal Chemistry|December 7, 2010
An imidazopiperidine series of CCR5 antagonists for the treatment of HIV: the discovery of N-{(1S)-1-(3-fluorophenyl)-3-[(3-endo)-3-(5-isobutyryl-2-methyl-4,5,6,7-tetrahydro-1H-imidazo[4,5-c]pyridin-1-yl)-8-azabicyclo[3.2.1]oct-8-yl]propyl}acetamide (PF-232798)Paul A Stupple, David V Batchelor, Martin Corless, et al.Journal of Medicinal Chemistry|April 10, 2019
Design and Identification of a Novel, Functionally Subtype Selective GABAA Positive Allosteric Modulator (PF-06372865)Robert M Owen, David Blakemore, Lishuang Cao, et al.Science (New York, N.Y.)|February 23, 2019
A pharmacological master key mechanism that unlocks the selectivity filter gate in K+ channelsMarcus Schewe, Han Sun, Ümit Mert, et al.Pageof 5