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Journal of Medicinal Chemistry|January 25, 2014
De-novo designed library of benzoylureas as inhibitors of BCL-XL: synthesis, structural and biochemical characterizationRyan M Brady, Amelia Vom, Michael J Roy, et al.Blood|June 26, 2016
Venetoclax responses of pediatric ALL xenografts reveal sensitivity of MLL-rearranged leukemiaSeong Lin Khaw, Santi Suryani, Kathryn Evans, et al.Nature|October 11, 2002
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosomeVanessa S Marsden, Liam O'Connor, Lorraine A O'Reilly, et al.Nature Immunology|July 10, 2007
Interleukin 15-mediated survival of natural killer cells is determined by interactions among Bim, Noxa and Mcl-1Nicholas D Huntington, Hamsa Puthalakath, Priscilla Gunn, et al.Arthritis & Rheumatology (Hoboken, N.J.)|November 25, 2014
Bcl-2 antagonists kill plasmacytoid dendritic cells from lupus-prone mice and dampen interferon-α productionYifan Zhan, Emma M Carrington, Hyun-Ja Ko, et al.Journal of Experimental & Clinical Cancer Research : CR|March 10, 2025
NONO interacts with nuclear PKM2 and directs histone H3 phosphorylation to promote triple-negative breast cancer metastasisQixiang Li, Hongfei Ci, Pengpeng Zhao, et al.Proceedings of the National Academy of Sciences of the United States of America|July 20, 2011
Sensitization of BCL-2-expressing breast tumors to chemotherapy by the BH3 mimetic ABT-737Samantha R Oakes, François Vaillant, Elgene Lim, et al.Nature Communications|November 12, 2021
Mesenchymal stromal cell apoptosis is required for their therapeutic functionSwee Heng Milon Pang, Joshua D'Rozario, Senora Mendonca, et al.Nature Microbiology|August 31, 2016
Eliminating Legionella by inhibiting BCL-XL to induce macrophage apoptosisMary Speir, Kate E Lawlor, Stefan P Glaser, et al.Cell Death & Disease|April 2, 2022
The Lck inhibitor, AMG-47a, blocks necroptosis and implicates RIPK1 in signalling downstream of MLKLAnnette V Jacobsen, Catia L Pierotti, Kym N Lowes, et al.Pageof 15