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Nature|March 4, 2011
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7Ingrid E Wertz, Saritha Kusam, Cynthia Lam, et al.
Nature Communications|September 10, 2021
TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growthTsz-Yin Chan, Christina M Egbert, Julia E Maxson, et al.
Genome Biology|November 12, 2021
Comprehensive characterization of single-cell full-length isoforms in human and mouse with long-read sequencingLuyi Tian, Jafar S Jabbari, Rachel Thijssen, et al.
Science Translational Medicine|March 20, 2015
Exploiting selective BCL-2 family inhibitors to dissect cell survival dependencies and define improved strategies for cancer therapyJoel D Leverson, Darren C Phillips, Michael J Mitten, et al.
Blood|April 7, 2021
Intact TP-53 function is essential for sustaining durable responses to BH3-mimetic drugs in leukemiasRachel Thijssen, Sarah T Diepstraten, Donia Moujalled, et al.
Nature Chemical Biology|October 9, 2019
A small molecule interacts with VDAC2 to block mouse BAK-driven apoptosisMark F van Delft, Stephane Chappaz, Yelena Khakham, et al.
Nature Medicine|January 8, 2013
ABT-199, a potent and selective BCL-2 inhibitor, achieves antitumor activity while sparing plateletsAndrew J Souers, Joel D Leverson, Erwin R Boghaert, et al.
Nature|October 28, 2016
The MCL1 inhibitor S63845 is tolerable and effective in diverse cancer modelsAndrás Kotschy, Zoltán Szlavik, James Murray, et al.
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