Showing results (1-10 of 575) with videos related to
Sort By:
Pageof 58
Trends in Genetics : TIG|August 18, 2004
Two direct repeats cause most human mtDNA deletionsDavid C Samuels, Eric A Schon, Patrick F ChinneryAmerican Journal of Human Genetics|November 4, 2008
The distribution of mitochondrial DNA heteroplasmy due to random genetic driftPassorn Wonnapinij, Patrick F Chinnery, David C SamuelsHuman Reproduction (Oxford, England)|January 9, 2013
Preventing the transmission of pathogenic mitochondrial DNA mutations: Can we achieve long-term benefits from germ-line gene transfer?David C Samuels, Passorn Wonnapinij, Patrick F ChinneryAmerican Journal of Human Genetics|April 6, 2010
Previous estimates of mitochondrial DNA mutation level variance did not account for sampling error: comparing the mtDNA genetic bottleneck in mice and humansPassorn Wonnapinij, Patrick F Chinnery, David C SamuelsAmerican Journal of Human Genetics|February 7, 2008
Selection against pathogenic mtDNA mutations in a stem cell population leads to the loss of the 3243A-->G mutation in bloodHarsha Karur Rajasimha, Patrick F Chinnery, David C SamuelsJournal of Theoretical Biology|April 26, 2003
A model of the nuclear control of mitochondrial DNA replicationGraham J Capps, David C Samuels, Patrick F ChinneryLancet (London, England)|November 5, 2002
Accumulation of mitochondrial DNA mutations in ageing, cancer, and mitochondrial disease: is there a common mechanism?Patrick F Chinnery, David C Samuels, Joanna Elson, et al.American Journal of Human Genetics|March 15, 2006
The power to detect disease associations with mitochondrial DNA haplogroupsDavid C Samuels, Andrew D Carothers, Robin Horton, et al.American Journal of Human Genetics|June 15, 2007
Normal levels of wild-type mitochondrial DNA maintain cytochrome c oxidase activity for two pathogenic mitochondrial DNA mutations but not for m.3243A-->GSteve E Durham, David C Samuels, Lynsey M Cree, et al.Nucleic Acids Research|October 8, 2003
A compositional segmentation of the human mitochondrial genome is related to heterogeneities in the guanine mutation rateDavid C Samuels, Richard J Boys, Daniel A Henderson, et al.Pageof 58