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Methods in Enzymology|January 29, 2013
Therapeutic rescue of misfolded/mistrafficked mutants: automation-friendly high-throughput assays for identification of pharmacoperone drugs of GPCRsDavid C Smithson, Jo Ann Janovick, P Michael ConnJournal of Biomolecular Screening|May 4, 2013
High-throughput screen for pharmacoperones of the vasopressin type 2 receptorP Michael Conn, Emery Smith, Peter Hodder, et al.The Journal of Biological Chemistry|March 12, 2010
Discovery of potent and selective inhibitors of Trypanosoma brucei ornithine decarboxylaseDavid C Smithson, Jeongmi Lee, Anang A Shelat, et al.Assay and Drug Development Technologies|January 21, 2010
Optimization of a non-radioactive high-throughput assay for decarboxylase enzymesDavid C Smithson, Anang A Shelat, Jeffrey Baldwin, et al.Bioorganic & Medicinal Chemistry Letters|June 11, 2013
Optimization of the electrophile of chloronitrobenzamide leads active against Trypanosoma bruceiJong Yeon Hwang, David C Smithson, Gloria Holbrook, et al.Bioorganic & Medicinal Chemistry Letters|February 5, 2010
Podophyllotoxin analogues active versus Trypanosoma bruceiMd Jashim Uddin, David C Smithson, Kristin M Brown, et al.Pharmacological Research|December 31, 2013
Transitioning pharmacoperones to therapeutic use: in vivo proof-of-principle and design of high throughput screensP Michael Conn, David C Smithson, Peter S Hodder, et al.Journal of Pharmaceutical Sciences|September 27, 2023
Development and Qualification of Analytical Methods to Support Low Concentration Drug Product in-use StudiesLaura Zheng, Gary Console, Christopher Wang, et al.Bioscience Reports|February 24, 2018
Cysteine modifiers suggest an allosteric inhibitory site on the CAL PDZ domainYu Zhao, Patrick R Cushing, David C Smithson, et al.Plos Neglected Tropical Diseases|December 30, 2017
Discovery of novel, orally bioavailable, antileishmanial compounds using phenotypic screeningDiana Ortiz, W Armand Guiguemde, Jared T Hammill, et al.Pageof 2