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The Journal of Biological Chemistry|August 14, 2020
Actin-binding compounds, previously discovered by FRET-based high-throughput screening, differentially affect skeletal and cardiac musclePiyali Guhathakurta, Lien A Phung, Ewa Prochniewicz, et al.
Proceedings of the National Academy of Sciences of the United States of America|November 22, 2012
Cardiac myosin binding protein-C restricts intrafilament torsional dynamics of actin in a phosphorylation-dependent mannerBrett A Colson, Inna N Rybakova, Ewa Prochniewicz, et al.
Journal of Molecular Biology|January 13, 2006
Structural dynamics of the actin-myosin interface by site-directed spectroscopyVicci L Korman, Sarah E B Anderson, Ewa Prochniewicz, et al.
Biorxiv : the Preprint Server for Biology|December 23, 2024
A FRET assay to quantitate levels of the human β-cardiac myosin interacting heads motif based on its near-atomic resolution structureRama Reddy Goluguri, Piyali Guhathakurta, Neha Nandwani, et al.
Journal of Molecular Biology|April 17, 2012
Impacts of dystrophin and utrophin domains on actin structural dynamics: implications for therapeutic designAva Yun Lin, Ewa Prochniewicz, Davin M Henderson, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 20, 2025
A FRET assay to monitor different structural states of human β-cardiac myosin including the interacting-heads motifRama Reddy Goluguri, Piyali Guhathakurta, Neha Nandwani, et al.
Biorxiv : the Preprint Server for Biology|March 3, 2023
FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulatorsOsha Roopnarine, Samantha L Yuen, Andrew R Thompson, et al.
Biomolecules|December 23, 2022
A Large-Scale High-Throughput Screen for Modulators of SERCA ActivityPhilip A Bidwell, Samantha L Yuen, Ji Li, et al.
European Journal of Medicinal Chemistry|December 6, 2025
Development of activators for SERCA2a for heart failure treatmentsMarzena Brinkmann, Tsung-Yun Kent Wong, Osha Roopnarine, et al.
Research Square|March 13, 2023
FRET assay for live-cell high-throughput screening of the cardiac SERCA pump yields multiple classes of small-molecule allosteric modulatorsOsha Roopnarine, Samantha L Yuen, Andrew R Thompson, et al.
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