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Journal of Medicinal Chemistry|October 17, 2022
Sebetralstat (KVD900): A Potent and Selective Small Molecule Plasma Kallikrein Inhibitor Featuring a Novel P1 Group as a Potential Oral On-Demand Treatment for Hereditary AngioedemaRebecca L Davie, Hannah J Edwards, D Michael Evans, et al.The Journal of Trauma|February 16, 2010
The Trauma Quality Improvement Program: pilot study and initial demonstration of feasibilityMark R Hemmila, Avery B Nathens, Shahid Shafi, et al.Bioorganic & Medicinal Chemistry Letters|November 11, 2006
Identification and optimisation of a series of substituted 5-(1H-pyrazol-3-yl)-thiophene-2-hydroxamic acids as potent histone deacetylase (HDAC) inhibitorsSteve Price, Walter Bordogna, Richard J Bull, et al.Bioorganic & Medicinal Chemistry Letters|March 20, 2010
Identification and hit-to-lead exploration of a novel series of histamine H4 receptor inverse agonistsSue Cramp, Hazel J Dyke, Christopher Higgs, et al.Bioorganic & Medicinal Chemistry Letters|January 30, 2008
1H-Pyrazolo[3,4-g]hexahydro-isoquinolines as selective glucocorticoid receptor antagonists with high functional activityRobin D Clark, Nicholas C Ray, Karen Williams, et al.Bioorganic & Medicinal Chemistry Letters|December 20, 2011
Novel heterocyclic DPP-4 inhibitors for the treatment of type 2 diabetesJon M Sutton, David E Clark, Stephen J Dunsdon, et al.Cancer Discovery|April 21, 2026
Pharmacological inhibition of PMS2 induces MMR deficiency and response to immune checkpoint blockadeJulian Blagg, Philippe Riou, Alexia Hervieu, et al.Pageof 9