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David F Ackerley

Showing results (71-80 of 83) with videos related to

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Cancer Gene Therapy|February 9, 2021
Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumoursAlexandra M Mowday, Ludwig J Dubois, Aleksandra M Kubiak, et al.
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association|November 19, 2023
Preparation, analysis and toxicity characterisation of the redox metabolites of the azo food dye tartrazineRuth Pay, Abigail V Sharrock, Riley Elder, et al.
Mbio|September 16, 2020
Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative InfectionsJanine N Copp, Daniel Pletzer, Alistair S Brown, et al.
Biochemical Pharmacology|July 26, 2016
Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapyAlexandra M Mowday, Amir Ashoorzadeh, Elsie M Williams, et al.
Biochemical Pharmacology|February 13, 2013
Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104AGareth A Prosser, Janine N Copp, Alexandra M Mowday, et al.
Pharmaceuticals (Basel, Switzerland)|December 28, 2021
Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3Maria R Abbattista, Amir Ashoorzadeh, Christopher P Guise, et al.
Cell Chemical Biology|October 28, 2023
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screeningMichelle H Rich, Abigail V Sharrock, Timothy S Mulligan, et al.
Biorxiv : the Preprint Server for Biology|March 30, 2023
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screeningMichelle H Rich, Abigail V Sharrock, Timothy S Mulligan, et al.
Development (Cambridge, England)|July 15, 2024
A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regenerationKevin Emmerich, John Hageter, Thanh Hoang, et al.
Biorxiv : the Preprint Server for Biology|December 4, 2023
Molecular regulation of retinal regeneration is context specificKevin Emmerich, John Hageter, Thanh Hoang, et al.
Pageof 9

Showing results (71-80 of 83) with videos related to

Sort By:
Pageof 9
Cancer Gene Therapy|February 9, 2021
Use of an optimised enzyme/prodrug combination for Clostridia directed enzyme prodrug therapy induces a significant growth delay in necrotic tumoursAlexandra M Mowday, Ludwig J Dubois, Aleksandra M Kubiak, et al.
Food and Chemical Toxicology : an International Journal Published for the British Industrial Biological Research Association|November 19, 2023
Preparation, analysis and toxicity characterisation of the redox metabolites of the azo food dye tartrazineRuth Pay, Abigail V Sharrock, Riley Elder, et al.
Mbio|September 16, 2020
Mechanistic Understanding Enables the Rational Design of Salicylanilide Combination Therapies for Gram-Negative InfectionsJanine N Copp, Daniel Pletzer, Alistair S Brown, et al.
Biochemical Pharmacology|July 26, 2016
Rational design of an AKR1C3-resistant analog of PR-104 for enzyme-prodrug therapyAlexandra M Mowday, Amir Ashoorzadeh, Elsie M Williams, et al.
Biochemical Pharmacology|February 13, 2013
Creation and screening of a multi-family bacterial oxidoreductase library to discover novel nitroreductases that efficiently activate the bioreductive prodrugs CB1954 and PR-104AGareth A Prosser, Janine N Copp, Alexandra M Mowday, et al.
Pharmaceuticals (Basel, Switzerland)|December 28, 2021
Restoring Tumour Selectivity of the Bioreductive Prodrug PR-104 by Developing an Analogue Resistant to Aerobic Metabolism by Human Aldo-Keto Reductase 1C3Maria R Abbattista, Amir Ashoorzadeh, Christopher P Guise, et al.
Cell Chemical Biology|October 28, 2023
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screeningMichelle H Rich, Abigail V Sharrock, Timothy S Mulligan, et al.
Biorxiv : the Preprint Server for Biology|March 30, 2023
A metagenomic library cloning strategy that promotes high-level expression of captured genes to enable efficient functional screeningMichelle H Rich, Abigail V Sharrock, Timothy S Mulligan, et al.
Development (Cambridge, England)|July 15, 2024
A large-scale CRISPR screen reveals context-specific genetic regulation of retinal ganglion cell regenerationKevin Emmerich, John Hageter, Thanh Hoang, et al.
Biorxiv : the Preprint Server for Biology|December 4, 2023
Molecular regulation of retinal regeneration is context specificKevin Emmerich, John Hageter, Thanh Hoang, et al.
Pageof 9