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Drug Metabolism Letters
|
July 16, 2009
Electronic and structural aspects of p450-mediated drug metabolism
David F V Lewis, Yuko Ito, Brian G Lake
Drug Discovery Today
|
June 9, 2004
Compound lipophilicity for substrate binding to human P450s in drug metabolism
David F V Lewis, Miriam N Jacobs, Maurice Dickins
Current Drug Metabolism
|
August 22, 2006
Investigating human P450s involved in drug metabolism via homology with high-resolution P450 crystal structures of the CYP2C subfamily
David F V Lewis, Yuko Ito, Peter S Goldfarb
Teratogenesis, Carcinogenesis, and Mutagenesis
|
March 5, 2003
A quantitative structure-activity relationship (QSAR) study of mutagenicity in several series of organic chemicals likely to be activated by cytochrome P450 enzymes
David F V Lewis, Costas Ioannides, Dennis V Parke
Toxicology in Vitro : an International Journal Published in Association with BIBRA
|
September 15, 2005
Metabolism of coumarin by human P450s: a molecular modelling study
David F V Lewis, Yuko Ito, Brian G Lake
Journal of Biochemical and Molecular Toxicology
|
March 5, 2003
A quantitative structure-activity relationship analysis on a series of alkyl benzenes metabolized by human cytochrome p450 2E1
David F V Lewis, Craig Sams, George D Loizou
Journal of Enzyme Inhibition and Medicinal Chemistry
|
June 23, 2006
Quantitative structure-activity relationships (QSars) in CYP3A4 inhibitors: the importance of lipophilic character and hydrogen bonding
David F V Lewis, Brian G Lake, Maurice Dickins
Current Medicinal Chemistry
|
October 5, 2006
Structural modelling of the human drug-metabolizing cytochromes P450
David F V Lewis, Yuko Ito, Peter S Goldfarb
Drug Metabolism and Drug Interactions
|
October 29, 2004
Substrates of human cytochromes P450 from families CYP1 and CYP2: analysis of enzyme selectivity and metabolism
David F V Lewis, Brian G Lake, Maurice Dickins
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
July 28, 2004
Quantitative structure-activity relationships within a homologous series of 7-alkoxyresorufins exhibiting activity towards CYP1A and CYP2B enzymes: molecular modelling studies on key members of the resorufin series with CYP2C5-derived models of human CYP1A1, CYP1A2, CYP2B6 and CYP3A4
David F V Lewis, Brian G Lake, M Dickins
Page
of 6
Search research articles
Search
Showing results (21-30 of 52) with videos related to
Sort By:
Page
of 6
Drug Metabolism Letters
|
July 16, 2009
Electronic and structural aspects of p450-mediated drug metabolism
David F V Lewis, Yuko Ito, Brian G Lake
Drug Discovery Today
|
June 9, 2004
Compound lipophilicity for substrate binding to human P450s in drug metabolism
David F V Lewis, Miriam N Jacobs, Maurice Dickins
Current Drug Metabolism
|
August 22, 2006
Investigating human P450s involved in drug metabolism via homology with high-resolution P450 crystal structures of the CYP2C subfamily
David F V Lewis, Yuko Ito, Peter S Goldfarb
Teratogenesis, Carcinogenesis, and Mutagenesis
|
March 5, 2003
A quantitative structure-activity relationship (QSAR) study of mutagenicity in several series of organic chemicals likely to be activated by cytochrome P450 enzymes
David F V Lewis, Costas Ioannides, Dennis V Parke
Toxicology in Vitro : an International Journal Published in Association with BIBRA
|
September 15, 2005
Metabolism of coumarin by human P450s: a molecular modelling study
David F V Lewis, Yuko Ito, Brian G Lake
Journal of Biochemical and Molecular Toxicology
|
March 5, 2003
A quantitative structure-activity relationship analysis on a series of alkyl benzenes metabolized by human cytochrome p450 2E1
David F V Lewis, Craig Sams, George D Loizou
Journal of Enzyme Inhibition and Medicinal Chemistry
|
June 23, 2006
Quantitative structure-activity relationships (QSars) in CYP3A4 inhibitors: the importance of lipophilic character and hydrogen bonding
David F V Lewis, Brian G Lake, Maurice Dickins
Current Medicinal Chemistry
|
October 5, 2006
Structural modelling of the human drug-metabolizing cytochromes P450
David F V Lewis, Yuko Ito, Peter S Goldfarb
Drug Metabolism and Drug Interactions
|
October 29, 2004
Substrates of human cytochromes P450 from families CYP1 and CYP2: analysis of enzyme selectivity and metabolism
David F V Lewis, Brian G Lake, Maurice Dickins
Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
July 28, 2004
Quantitative structure-activity relationships within a homologous series of 7-alkoxyresorufins exhibiting activity towards CYP1A and CYP2B enzymes: molecular modelling studies on key members of the resorufin series with CYP2C5-derived models of human CYP1A1, CYP1A2, CYP2B6 and CYP3A4
David F V Lewis, Brian G Lake, M Dickins
Page
of 6