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Science (New York, N.Y.)
|
June 5, 2010
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
Tunda Hidvegi, Michael Ewing, Pamela Hale, et al.
Plos One
|
October 30, 2015
Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin Deficiency
Erin E Cummings, Linda P O'Reilly, Dale E King, et al.
Plos One
|
February 6, 2014
Fluphenazine reduces proteotoxicity in C. elegans and mammalian models of alpha-1-antitrypsin deficiency
Jie Li, Stephen C Pak, Linda P O'Reilly, et al.
Research Square
|
May 22, 2023
Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease
Seong Won Lee, Young Mi Oh, Matheus B Victor, et al.
Plos One
|
January 24, 2019
An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z
Yan Wang, Murat C Cobanoglu, Jie Li, et al.
The Journal of Clinical Investigation
|
April 21, 2011
Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes
Jianqiang Ding, Govardhana R Yannam, Namita Roy-Chowdhury, et al.
Autophagy Reports
|
July 29, 2024
A fluorescent reporter for rapid assessment of autophagic flux reveals unique autophagy signatures during <i>C. elegans</i> post-embryonic development and identifies compounds that modulate autophagy
Zachary D Dawson, Hemalatha Sundaramoorthi, Suk Regmi, et al.
Human Molecular Genetics
|
May 20, 2014
A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency
Linda P O'Reilly, Olivia S Long, Murat C Cobanoglu, et al.
Nature Communications
|
March 31, 2026
A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia
Farzaneh S Mirfakhar, Jacob A Marsh, Chihiro Sato, et al.
Hepatology Communications
|
February 27, 2023
Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency
Yanfeng Li, Chandan Guha, Patrik Asp, et al.
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of 8
Search research articles
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Showing results (51-60 of 74) with videos related to
Sort By:
Page
of 8
Science (New York, N.Y.)
|
June 5, 2010
An autophagy-enhancing drug promotes degradation of mutant alpha1-antitrypsin Z and reduces hepatic fibrosis
Tunda Hidvegi, Michael Ewing, Pamela Hale, et al.
Plos One
|
October 30, 2015
Deficient and Null Variants of SERPINA1 Are Proteotoxic in a Caenorhabditis elegans Model of α1-Antitrypsin Deficiency
Erin E Cummings, Linda P O'Reilly, Dale E King, et al.
Plos One
|
February 6, 2014
Fluphenazine reduces proteotoxicity in C. elegans and mammalian models of alpha-1-antitrypsin deficiency
Jie Li, Stephen C Pak, Linda P O'Reilly, et al.
Research Square
|
May 22, 2023
Longitudinal modeling of human neuronal aging identifies RCAN1-TFEB pathway contributing to neurodegeneration of Huntington's disease
Seong Won Lee, Young Mi Oh, Matheus B Victor, et al.
Plos One
|
January 24, 2019
An analog of glibenclamide selectively enhances autophagic degradation of misfolded α1-antitrypsin Z
Yan Wang, Murat C Cobanoglu, Jie Li, et al.
The Journal of Clinical Investigation
|
April 21, 2011
Spontaneous hepatic repopulation in transgenic mice expressing mutant human α1-antitrypsin by wild-type donor hepatocytes
Jianqiang Ding, Govardhana R Yannam, Namita Roy-Chowdhury, et al.
Autophagy Reports
|
July 29, 2024
A fluorescent reporter for rapid assessment of autophagic flux reveals unique autophagy signatures during <i>C. elegans</i> post-embryonic development and identifies compounds that modulate autophagy
Zachary D Dawson, Hemalatha Sundaramoorthi, Suk Regmi, et al.
Human Molecular Genetics
|
May 20, 2014
A genome-wide RNAi screen identifies potential drug targets in a C. elegans model of α1-antitrypsin deficiency
Linda P O'Reilly, Olivia S Long, Murat C Cobanoglu, et al.
Nature Communications
|
March 31, 2026
A pathogenic Tau mutation drives autophagy-lysosome dysfunction that limits Tau degradation in a model of frontotemporal dementia
Farzaneh S Mirfakhar, Jacob A Marsh, Chihiro Sato, et al.
Hepatology Communications
|
February 27, 2023
Resolution of hepatic fibrosis after ZFN-mediated gene editing in the PiZ mouse model of human α1-antitrypsin deficiency
Yanfeng Li, Chandan Guha, Patrik Asp, et al.
Page
of 8