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David H Perlmutter

Showing results (61-70 of 74) with videos related to

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Nature Aging|December 8, 2023
Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington's disease neurodegenerationSeong Won Lee, Young Mi Oh, Matheus B Victor, et al.
Plos One|November 25, 2010
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZSager J Gosai, Joon Hyeok Kwak, Cliff J Luke, et al.
Nature Neuroscience|October 27, 2022
Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagyYoung Mi Oh, Seong Won Lee, Woo Kyung Kim, et al.
Gastroenterology|March 18, 2022
Regulation of PGC1α Downstream of the Insulin Signaling Pathway Plays a Role in the Hepatic Proteotoxicity of Mutant α1-Antitrypsin Deficiency Variant ZDavid A Rudnick, Jiansheng Huang, Tunda Hidvegi, et al.
Cellular and Molecular Gastroenterology and Hepatology|February 9, 2024
Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin DeficiencyJie Li, Francesca Moretti, Tunda Hidvegi, et al.
Hepatology (Baltimore, Md.)|February 19, 2015
Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiencyEdgar N Tafaleng, Souvik Chakraborty, Bing Han, et al.
Hepatology (Baltimore, Md.)|April 1, 2024
Variants in autophagy genes MTMR12 and FAM134A are putative modifiers of the hepatic phenotype in α1-antitrypsin deficiencyEdgar N Tafaleng, Jie Li, Yan Wang, et al.
Autophagy|June 19, 2013
Functions of autophagy in normal and diseased liverMark J Czaja, Wen-Xing Ding, Terrence M Donohue, et al.
Human Molecular Genetics|May 20, 2014
A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnoverOlivia S Long, Joshua A Benson, Joon Hyeok Kwak, et al.
The Journal of Biological Chemistry|October 24, 2015
Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell ProteinopathyTunda Hidvegi, Donna B Stolz, John F Alcorn, et al.
Pageof 8

Showing results (61-70 of 74) with videos related to

Sort By:
Pageof 8
Nature Aging|December 8, 2023
Longitudinal modeling of human neuronal aging reveals the contribution of the RCAN1-TFEB pathway to Huntington's disease neurodegenerationSeong Won Lee, Young Mi Oh, Matheus B Victor, et al.
Plos One|November 25, 2010
Automated high-content live animal drug screening using C. elegans expressing the aggregation prone serpin α1-antitrypsin ZSager J Gosai, Joon Hyeok Kwak, Cliff J Luke, et al.
Nature Neuroscience|October 27, 2022
Age-related Huntington's disease progression modeled in directly reprogrammed patient-derived striatal neurons highlights impaired autophagyYoung Mi Oh, Seong Won Lee, Woo Kyung Kim, et al.
Gastroenterology|March 18, 2022
Regulation of PGC1α Downstream of the Insulin Signaling Pathway Plays a Role in the Hepatic Proteotoxicity of Mutant α1-Antitrypsin Deficiency Variant ZDavid A Rudnick, Jiansheng Huang, Tunda Hidvegi, et al.
Cellular and Molecular Gastroenterology and Hepatology|February 9, 2024
Multiple Genes Core to ERAD, Macroautophagy and Lysosomal Degradation Pathways Participate in the Proteostasis Response in α1-Antitrypsin DeficiencyJie Li, Francesca Moretti, Tunda Hidvegi, et al.
Hepatology (Baltimore, Md.)|February 19, 2015
Induced pluripotent stem cells model personalized variations in liver disease resulting from α1-antitrypsin deficiencyEdgar N Tafaleng, Souvik Chakraborty, Bing Han, et al.
Hepatology (Baltimore, Md.)|April 1, 2024
Variants in autophagy genes MTMR12 and FAM134A are putative modifiers of the hepatic phenotype in α1-antitrypsin deficiencyEdgar N Tafaleng, Jie Li, Yan Wang, et al.
Autophagy|June 19, 2013
Functions of autophagy in normal and diseased liverMark J Czaja, Wen-Xing Ding, Terrence M Donohue, et al.
Human Molecular Genetics|May 20, 2014
A C. elegans model of human α1-antitrypsin deficiency links components of the RNAi pathway to misfolded protein turnoverOlivia S Long, Joshua A Benson, Joon Hyeok Kwak, et al.
The Journal of Biological Chemistry|October 24, 2015
Enhancing Autophagy with Drugs or Lung-directed Gene Therapy Reverses the Pathological Effects of Respiratory Epithelial Cell ProteinopathyTunda Hidvegi, Donna B Stolz, John F Alcorn, et al.
Pageof 8