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Toxicology and Applied Pharmacology|July 22, 2008
Gene expression profiles modulated by the human carcinogen aristolochic acid I in human cancer cells and their dependence on TP53Maria L Simões, Sarah L Hockley, Tanja Schwerdtle, et al.
Toxicology|March 11, 2008
The environmental pollutant and carcinogen 3-nitrobenzanthrone induces cytochrome P450 1A1 and NAD(P)H:quinone oxidoreductase in rat lung and kidney, thereby enhancing its own genotoxicityMarie Stiborová, Helena Dracínská, Jana Mizerovská, et al.
Mutation Research. Genetic Toxicology and Environmental Mutagenesis|October 3, 2013
The GSTM1null (deletion) and MGMT84 rs12917 (Phe/Phe) haplotype are associated with bulky DNA adduct levels in human leukocytesEdith Molina, Rebeca Pérez-Morales, Julieta Rubio, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|May 23, 2006
The environmental pollutant and carcinogen 3-nitrobenzanthrone and its human metabolite 3-aminobenzanthrone are potent inducers of rat hepatic cytochromes P450 1A1 and -1A2 and NAD(P)H:quinone oxidoreductaseMarie Stiborová, Helena Dracínská, Jana Hájková, et al.
Archives of Toxicology|November 16, 2014
Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanismLaura E Wohak, Annette M Krais, Jill E Kucab, et al.
Toxicology and Applied Pharmacology|November 3, 2007
Role of hepatic cytochromes P450 in bioactivation of the anticancer drug ellipticine: studies with the hepatic NADPH:cytochrome P450 reductase null mouseMarie Stiborová, Volker M Arlt, Colin J Henderson, et al.
Toxicology|February 23, 2018
The impact of chemotherapeutic drugs on the CYP1A1-catalysed metabolism of the environmental carcinogen benzo[a]pyrene: Effects in human colorectal HCT116 TP53(+/+), TP53(+/-) and TP53(-/-) cellsAlexandra J Willis, Radek Indra, Laura E Wohak, et al.
International Journal of Cancer|May 13, 2003
Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cellsVolker M Arlt, Hansruedi Glatt, Eva Muckel, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|November 17, 2011
Bioactivation versus detoxication of the urothelial carcinogen aristolochic acid I by human cytochrome P450 1A1 and 1A2Marie Stiborová, Katerina Levová, Frantisek Bárta, et al.
Chemical Research in Toxicology|June 21, 2005
Synthesis, characterization, and 32p-postlabeling analysis of DNA adducts derived from the environmental contaminant 3-nitrobenzanthroneMartin R Osborne, Volker M Arlt, Christian Kliem, et al.
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