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Journal of Structural Biology|April 30, 2003
A fully integrated protein crystallization platform for small-molecule drug discoveryDavid Hosfield, John Palan, Mark Hilgers, et al.Biorxiv : the Preprint Server for Biology|August 7, 2023
Evaluating steroid hormone receptor interactions using the live-cell NanoBRET proximity assayRosemary J Huggins, David Hosfield, Amira Ishag-Osman, et al.Bioorganic & Medicinal Chemistry Letters|May 18, 2017
Discovery of potent and orally active 1,4-disubstituted indazoles as novel allosteric glucokinase activatorsZacharia S Cheruvallath, Stephen L Gwaltney, Mark Sabat, et al.Bioorganic & Medicinal Chemistry Letters|February 26, 2013
Design, synthesis and SAR of novel glucokinase activatorsZacharia S Cheruvallath, Stephen L Gwaltney, Mark Sabat, et al.Proceedings of the National Academy of Sciences of the United States of America|January 5, 2002
Cloning, expression, and characterization of a nitric oxide synthase protein from Deinococcus radioduransSubrata Adak, Alexandrine M Bilwes, Koustubh Panda, et al.Journal of Molecular Biology|April 13, 2010
X-ray structures of the LXRalpha LBD in its homodimeric form and implications for heterodimer signalingXavier Fradera, Diep Vu, Olaf Nimz, et al.Bioorganic & Medicinal Chemistry Letters|February 8, 2017
Structure-based design and SAR development of 5,6-dihydroimidazolo[1,5-f]pteridine derivatives as novel Polo-like kinase-1 inhibitorsAndre Kiryanov, Srinivasa Natala, Benjamin Jones, et al.Proceedings of the National Academy of Sciences of the United States of America|October 6, 2025
ProT-VAE: Protein Transformer Variational AutoEncoder for functional protein designEmre Sevgen, Joshua Moller, Adrian Lange, et al.Bioorganic & Medicinal Chemistry Letters|May 14, 2013
Discovery of TAK-960: an orally available small molecule inhibitor of polo-like kinase 1 (PLK1)Zhe Nie, Victoria Feher, Srinivasa Natala, et al.Journal of Medicinal Chemistry|October 9, 2020
Discovery of CC-90011: A Potent and Selective Reversible Inhibitor of Lysine Specific Demethylase 1 (LSD1)Toufike Kanouni, Christophe Severin, Robert W Cho, et al.Pageof 1