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David J Edmonds

Showing results (21-30 of 37) with videos related to

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The Journal of Biological Chemistry|May 27, 2016
Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in VitroJoakim E Swedberg, Christina I Schroeder, Justin M Mitchell, et al.
European Journal of Medicinal Chemistry|September 10, 2015
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonistsJoakim E Swedberg, Christina I Schroeder, Justin M Mitchell, et al.
Angewandte Chemie (International Ed. in English)|September 16, 2014
Improving on nature: making a cyclic heptapeptide orally bioavailableDaniel S Nielsen, Huy N Hoang, Rink-Jan Lohman, et al.
European Journal of Medicinal Chemistry|November 9, 2016
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signalingFabien Plisson, Timothy A Hill, Justin M Mitchell, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2023
6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptorGary E Aspnes, Scott W Bagley, Steven B Coffey, et al.
Journal of Medicinal Chemistry|July 24, 2018
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)Tim F Ryder, Matthew F Calabrese, Gregory S Walker, et al.
The Journal of Organic Chemistry|November 7, 2012
Synthesis of spiropiperidine lactam acetyl-CoA carboxylase inhibitorsKim Huard, Scott W Bagley, Elnaz Menhaji-Klotz, et al.
ACS Medicinal Chemistry Letters|October 18, 2023
Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-LifeKevin J Filipski, David J Edmonds, Michelle R Garnsey, et al.
Journal of Medicinal Chemistry|April 4, 2015
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) AgonistsHuy N Hoang, Kun Song, Timothy A Hill, et al.
Journal of Medicinal Chemistry|August 29, 2013
Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structureDavid A Griffith, Robert L Dow, Kim Huard, et al.
Pageof 4

Showing results (21-30 of 37) with videos related to

Sort By:
Pageof 4
The Journal of Biological Chemistry|May 27, 2016
Truncated Glucagon-like Peptide-1 and Exendin-4 α-Conotoxin pl14a Peptide Chimeras Maintain Potency and α-Helicity and Reveal Interactions Vital for cAMP Signaling in VitroJoakim E Swedberg, Christina I Schroeder, Justin M Mitchell, et al.
European Journal of Medicinal Chemistry|September 10, 2015
Cyclic alpha-conotoxin peptidomimetic chimeras as potent GLP-1R agonistsJoakim E Swedberg, Christina I Schroeder, Justin M Mitchell, et al.
Angewandte Chemie (International Ed. in English)|September 16, 2014
Improving on nature: making a cyclic heptapeptide orally bioavailableDaniel S Nielsen, Huy N Hoang, Rink-Jan Lohman, et al.
European Journal of Medicinal Chemistry|November 9, 2016
Helixconstraints and amino acid substitution in GLP-1 increase cAMP and insulin secretion but not beta-arrestin 2 signalingFabien Plisson, Timothy A Hill, Justin M Mitchell, et al.
Bioorganic & Medicinal Chemistry Letters|August 17, 2023
6-Azaspiro[2.5]octanes as small molecule agonists of the human glucagon-like peptide-1 receptorGary E Aspnes, Scott W Bagley, Steven B Coffey, et al.
Journal of Medicinal Chemistry|July 24, 2018
Acyl Glucuronide Metabolites of 6-Chloro-5-[4-(1-hydroxycyclobutyl)phenyl]-1 H-indole-3-carboxylic Acid (PF-06409577) and Related Indole-3-carboxylic Acid Derivatives are Direct Activators of Adenosine Monophosphate-Activated Protein Kinase (AMPK)Tim F Ryder, Matthew F Calabrese, Gregory S Walker, et al.
The Journal of Organic Chemistry|November 7, 2012
Synthesis of spiropiperidine lactam acetyl-CoA carboxylase inhibitorsKim Huard, Scott W Bagley, Elnaz Menhaji-Klotz, et al.
ACS Medicinal Chemistry Letters|October 18, 2023
Design of Next-Generation DGAT2 Inhibitor PF-07202954 with Longer Predicted Half-LifeKevin J Filipski, David J Edmonds, Michelle R Garnsey, et al.
Journal of Medicinal Chemistry|April 4, 2015
Short Hydrophobic Peptides with Cyclic Constraints Are Potent Glucagon-like Peptide-1 Receptor (GLP-1R) AgonistsHuy N Hoang, Kun Song, Timothy A Hill, et al.
Journal of Medicinal Chemistry|August 29, 2013
Spirolactam-based acetyl-CoA carboxylase inhibitors: toward improved metabolic stability of a chromanone lead structureDavid A Griffith, Robert L Dow, Kim Huard, et al.
Pageof 4