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Frontiers in Physiology|May 13, 2022
Identifying Acute Cardiac Hazard in Early Drug Discovery Using a Calcium Transient High-Throughput Assay in Human-Induced Pluripotent Stem Cell-Derived CardiomyocytesHua Rong Lu, Mohamed Kreir, Van Ammel Karel, et al.Stem Cell Reports|December 13, 2018
Development of a Human iPSC Cardiomyocyte-Based Scoring System for Cardiac Hazard Identification in Early Drug Safety De-riskingIvan Kopljar, Hua Rong Lu, Karel Van Ammel, et al.Pediatric Research|August 7, 2023
Baseline azithromycin resistance in the gut microbiota of preterm born infantsDavid J Gallacher, Lei Zhang, Ali F Aboklaish, et al.Annals of Noninvasive Electrocardiology : the Official Journal of the International Society for Holter and Noninvasive Electrocardiology, Inc|August 26, 2015
Evaluation of Index of Cardio-Electrophysiological Balance (iCEB) as a New Biomarker for the Identification of Patients at Increased Arrhythmic RiskTomas Robyns, Hua Rong Lu, David J Gallacher, et al.Stem Cells Translational Medicine|April 2, 2016
Functional and Transcriptional Characterization of Histone Deacetylase Inhibitor-Mediated Cardiac Adverse Effects in Human Induced Pluripotent Stem Cell-Derived CardiomyocytesIvan Kopljar, David J Gallacher, An De Bondt, et al.Proceedings of the National Academy of Sciences of the United States of America|May 22, 2013
Experimentally calibrated population of models predicts and explains intersubject variability in cardiac cellular electrophysiologyOliver J Britton, Alfonso Bueno-Orovio, Karel Van Ammel, et al.Clinical Pharmacology and Therapeutics|December 7, 2020
Utility of Normalized TdP Score System in Drug Proarrhythmic Potential Assessment: A Blinded in vitro Study of CiPA DrugsTengxian Liu, Jiang Liu, Hua Rong Lu, et al.Journal of Pharmacological and Toxicological Methods|December 3, 2014
Characterization of an anesthetized dog model of transient cardiac ischemia and rapid pacing: a pilot study for preclinical assessment of the potential for proarrhythmic risk of novel drug candidatesBruce P Damiano, Henk J van der Linde, Bruno Van Deuren, et al.Toxicological Sciences : an Official Journal of the Society of Toxicology|September 12, 2015
High Throughput Measurement of Ca++ Dynamics in Human Stem Cell-Derived Cardiomyocytes by Kinetic Image Cytometery: A Cardiac Risk Assessment Characterization Using a Large Panel of Cardioactive and Inactive CompoundsHua Rong Lu, Ross Whittaker, Jeffrey H Price, et al.Journal of Pharmacological and Toxicological Methods|May 9, 2009
The fentanyl/etomidate-anaesthetised beagle (FEAB) dog: a versatile in vivo model in cardiovascular safety researchBruno Van Deuren, Karel Van Ammel, Yves Somers, et al.Pageof 7