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Journal of Medicinal Chemistry|May 17, 2018
Discovery of Orally Bioavailable, Quinoline-Based Aldehyde Dehydrogenase 1A1 (ALDH1A1) Inhibitors with Potent Cellular ActivityShyh-Ming Yang, Natalia J Martinez, Adam Yasgar, et al.
Chemistry & Biology|January 29, 2013
A small molecule inhibitor of the BLM helicase modulates chromosome stability in human cellsGiang Huong Nguyen, Thomas S Dexheimer, Andrew S Rosenthal, et al.
Molecular Oncology|June 2, 2014
Genomic and protein expression analysis reveals flap endonuclease 1 (FEN1) as a key biomarker in breast and ovarian cancerTarek M A Abdel-Fatah, Roslin Russell, Nada Albarakati, et al.
Science Translational Medicine|February 16, 2018
Irreversible inhibition of cytosolic thioredoxin reductase 1 as a mechanistic basis for anticancer therapyWilliam C Stafford, Xiaoxiao Peng, Maria Hägg Olofsson, et al.
Molecular Cancer Therapeutics|November 14, 2018
Predicting Novel Therapies and Targets: Regulation of Notch3 by the Bromodomain Protein BRD4Alejandro Villar-Prados, Sherry Y Wu, Karem A Court, et al.
Journal of Medicinal Chemistry|March 15, 2018
Insights into the Action of Inhibitor Enantiomers against Histone Lysine Demethylase 5AJohn R Horton, Xu Liu, Lizhen Wu, et al.
Journal of Medicinal Chemistry|November 6, 2018
Structure-Based Engineering of Irreversible Inhibitors against Histone Lysine Demethylase KDM5AJohn R Horton, Clayton B Woodcock, Qin Chen, et al.
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