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Molecular and Cellular Endocrinology|April 17, 2012
Integration of pro-inflammatory cytokines, 12-lipoxygenase and NOX-1 in pancreatic islet beta cell dysfunctionJessica R Weaver, Theodore R Holman, Yumi Imai, et al.Plos One|November 13, 2010
High-affinity inhibitors of human NAD-dependent 15-hydroxyprostaglandin dehydrogenase: mechanisms of inhibition and structure-activity relationshipsFrank H Niesen, Lena Schultz, Ajit Jadhav, et al.Journal of Medicinal Chemistry|November 14, 2009
Quantitative analyses of aggregation, autofluorescence, and reactivity artifacts in a screen for inhibitors of a thiol proteaseAjit Jadhav, Rafaela S Ferreira, Carleen Klumpp, et al.Retrovirology|February 17, 2016
Rilpivirine analogs potently inhibit drug-resistant HIV-1 mutantsSteven J Smith, Gary T Pauly, Aamir Akram, et al.Molecular Carcinogenesis|April 14, 2015
Inhibitors of the apurinic/apyrimidinic endonuclease 1 (APE1)/nucleophosmin (NPM1) interaction that display anti-tumor propertiesMattia Poletto, Matilde C Malfatti, Dorjbal Dorjsuren, et al.Anesthesiology|January 21, 2015
Discovery of a novel general anesthetic chemotype using high-throughput screeningAndrew R McKinstry-Wu, Weiming Bu, Ganesha Rai, et al.Bioorganic & Medicinal Chemistry Letters|April 1, 2011
Potent and selective small molecule inhibitors of specific isoforms of Cdc2-like kinases (Clk) and dual specificity tyrosine-phosphorylation-regulated kinases (Dyrk)Andrew S Rosenthal, Cordelle Tanega, Min Shen, et al.Journal of Medicinal Chemistry|June 15, 2010
Complementarity between a docking and a high-throughput screen in discovering new cruzain inhibitorsRafaela S Ferreira, Anton Simeonov, Ajit Jadhav, et al.Nature Communications|November 13, 2014
Suppression of the FOXM1 transcriptional programme via novel small molecule inhibitionMichael V Gormally, Thomas S Dexheimer, Giovanni Marsico, et al.Arteriosclerosis, Thrombosis, and Vascular Biology|August 5, 2017
First Selective 12-LOX Inhibitor, ML355, Impairs Thrombus Formation and Vessel Occlusion In Vivo With Minimal Effects on HemostasisReheman Adili, Benjamin E Tourdot, Katherine Mast, et al.Pageof 11