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David J Richard

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Chemical Communications (Cambridge, England)|September 16, 2004
Cyclopeptide alkaloids: chemistry and biologyMadeleine M Joullié, David J Richard
Expert Opinion on Therapeutic Patents|May 20, 2011
Recent advances in the discovery of small-molecule ATP competitive mTOR inhibitors: a patent reviewArie Zask, Jeroen C Verheijen, David J Richard
Current Opinion in Drug Discovery & Development|July 3, 2010
Recent advances in the development of selective, ATP-competitive inhibitors of mTORDavid J Richard, Jeroen C Verheijen, Arie Zask
Proceedings of the National Academy of Sciences of the United States of America|May 14, 2004
Synthetic studies of roquefortine C: synthesis of isoroquefortine C and a heterocycleDavid J Richard, Bruno Schiavi, Madeleine M Joullié
The Journal of Organic Chemistry|February 22, 2002
Total synthesis of isoroquefortine CBruno M Schiavi, David J Richard, Madeleine M Joullié
Bioorganic & Medicinal Chemistry Letters|March 13, 2010
Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3KalphaDavid J Richard, Jeroen C Verheijen, Ker Yu, et al.
Bioorganic & Medicinal Chemistry Letters|March 13, 2010
2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stabilityJeroen C Verheijen, David J Richard, Kevin Curran, et al.
Bioorganic & Medicinal Chemistry Letters|March 16, 2010
Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitorsArie Zask, Jeroen C Verheijen, David J Richard, et al.
Bioorganic & Medicinal Chemistry Letters|November 10, 2009
Incorporation of water-solubilizing groups in pyrazolopyrimidine mTOR inhibitors: discovery of highly potent and selective analogs with improved human microsomal stabilityDavid J Richard, Jeroen C Verheijen, Kevin Curran, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2010
Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 1-substituentKevin J Curran, Jeroen C Verheijen, Joshua Kaplan, et al.
Pageof 2

Showing results (1-10 of 15) with videos related to

Sort By:
Pageof 2
Chemical Communications (Cambridge, England)|September 16, 2004
Cyclopeptide alkaloids: chemistry and biologyMadeleine M Joullié, David J Richard
Expert Opinion on Therapeutic Patents|May 20, 2011
Recent advances in the discovery of small-molecule ATP competitive mTOR inhibitors: a patent reviewArie Zask, Jeroen C Verheijen, David J Richard
Current Opinion in Drug Discovery & Development|July 3, 2010
Recent advances in the development of selective, ATP-competitive inhibitors of mTORDavid J Richard, Jeroen C Verheijen, Arie Zask
Proceedings of the National Academy of Sciences of the United States of America|May 14, 2004
Synthetic studies of roquefortine C: synthesis of isoroquefortine C and a heterocycleDavid J Richard, Bruno Schiavi, Madeleine M Joullié
The Journal of Organic Chemistry|February 22, 2002
Total synthesis of isoroquefortine CBruno M Schiavi, David J Richard, Madeleine M Joullié
Bioorganic & Medicinal Chemistry Letters|March 13, 2010
Triazines incorporating (R)-3-methylmorpholine are potent inhibitors of the mammalian target of rapamycin (mTOR) with selectivity over PI3KalphaDavid J Richard, Jeroen C Verheijen, Ker Yu, et al.
Bioorganic & Medicinal Chemistry Letters|March 13, 2010
2-Arylureidophenyl-4-(3-oxa-8-azabicyclo[3.2.1]octan-8-yl)triazines as highly potent and selective ATP competitive mTOR inhibitors: optimization of human microsomal stabilityJeroen C Verheijen, David J Richard, Kevin Curran, et al.
Bioorganic & Medicinal Chemistry Letters|March 16, 2010
Discovery of 2-ureidophenyltriazines bearing bridged morpholines as potent and selective ATP-competitive mTOR inhibitorsArie Zask, Jeroen C Verheijen, David J Richard, et al.
Bioorganic & Medicinal Chemistry Letters|November 10, 2009
Incorporation of water-solubilizing groups in pyrazolopyrimidine mTOR inhibitors: discovery of highly potent and selective analogs with improved human microsomal stabilityDavid J Richard, Jeroen C Verheijen, Kevin Curran, et al.
Bioorganic & Medicinal Chemistry Letters|January 22, 2010
Pyrazolopyrimidines as highly potent and selective, ATP-competitive inhibitors of the mammalian target of rapamycin (mTOR): optimization of the 1-substituentKevin J Curran, Jeroen C Verheijen, Joshua Kaplan, et al.
Pageof 2