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Journal of Biomolecular Screening|February 8, 2011
Optimized high-throughput screen for hepatitis C virus translation inhibitorsKatherine E Berry, Betty Peng, David Koditek, et al.
The Journal of Biological Chemistry|January 30, 2015
Structural, biochemical, and biophysical characterization of idelalisib binding to phosphoinositide 3-kinase δJohn R Somoza, David Koditek, Armando G Villaseñor, et al.
Biochemistry|March 17, 2015
Functional label-free assays for characterizing the in vitro mechanism of action of small molecule modulators of capsid assemblyLatesh Lad, Sheila Clancy, David Koditek, et al.
Journal of Biomolecular Screening|April 28, 2011
Screening and identification of a novel class of TGF-β type 1 receptor kinase inhibitorQ Khai Huynh, Sarah J Wise, Keith A Koch, et al.
Journal of Medicinal Chemistry|July 18, 2018
Atropisomerism by Design: Discovery of a Selective and Stable Phosphoinositide 3-Kinase (PI3K) β InhibitorJayaraman Chandrasekhar, Ryan Dick, Joshua Van Veldhuizen, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Discovery of an Atropisomeric PI3Kβ Selective Inhibitor through Optimization of the Hinge Binding MotifStephane Perreault, Fatima Arjmand, Jayaraman Chandrasekhar, et al.
Journal of Medicinal Chemistry|January 21, 2017
Discovery of a Phosphoinositide 3-Kinase (PI3K) β/δ Inhibitor for the Treatment of Phosphatase and Tensin Homolog (PTEN) Deficient Tumors: Building PI3Kβ Potency in a PI3Kδ-Selective Template by Targeting Nonconserved Asp856Stephane Perreault, Jayaraman Chandrasekhar, Zhi-Hua Cui, et al.
Cancer Research|September 16, 2022
A Probody T Cell-Engaging Bispecific Antibody Targeting EGFR and CD3 Inhibits Colon Cancer Growth with Limited ToxicityLeila M Boustany, Sherry L LaPorte, Laurie Wong, et al.
Biochimica Et Biophysica Acta|May 6, 2009
Suppression of HDAC nuclear export and cardiomyocyte hypertrophy by novel irreversible inhibitors of CRM1Lauren Monovich, Keith A Koch, Robin Burgis, et al.
Journal of Medicinal Chemistry|September 24, 2016
Discovery of Orally Efficacious Phosphoinositide 3-Kinase δ Inhibitors with Improved Metabolic StabilityLeena Patel, Jayaraman Chandrasekhar, Jerry Evarts, et al.
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