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David Komander

Showing results (121-130 of 145) with videos related to

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Plos Pathogens|July 16, 2020
Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppressionLinda J Visser, Chiara Aloise, Kirby N Swatek, et al.
Molecular Cell|February 18, 2018
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2Alessandro Annibaldi, Sidonie Wicky John, Tom Vanden Berghe, et al.
Nature Chemical Biology|May 17, 2016
A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymesMonique P C Mulder, Katharina Witting, Ilana Berlin, et al.
The EMBO Journal|October 26, 2021
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosisZikou Liu, Laura F Dagley, Kristy Shield-Artin, et al.
Biochimica Et Biophysica Acta. General Subjects|October 3, 2020
The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathwayValentine Spagnol, Caio A B Oliveira, Suzanne J Randle, et al.
Biorxiv : the Preprint Server for Biology|August 6, 2025
Differentiation of <i>Toxoplasma</i> into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligaseAlessandro D Uboldi, Sachin Khurana, Amalie A Jaywickrama, et al.
Nature|October 13, 2016
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase CezanneTycho E T Mevissen, Yogesh Kulathu, Monique P C Mulder, et al.
Molecular and Cellular Biology|March 19, 2008
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistanceJose R Bayascas, Stephan Wullschleger, Kei Sakamoto, et al.
Nature Communications|March 25, 2023
Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymesBianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, et al.
EMBO Reports|July 11, 2024
PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCF<sup>FBXL4</sup>Giang Thanh Nguyen-Dien, Brendan Townsend, Prajakta Gosavi Kulkarni, et al.
Pageof 15

Showing results (121-130 of 145) with videos related to

Sort By:
Pageof 15
Plos Pathogens|July 16, 2020
Dissecting distinct proteolytic activities of FMDV Lpro implicates cleavage and degradation of RLR signaling proteins, not its deISGylase/DUB activity, in type I interferon suppressionLinda J Visser, Chiara Aloise, Kirby N Swatek, et al.
Molecular Cell|February 18, 2018
Ubiquitin-Mediated Regulation of RIPK1 Kinase Activity Independent of IKK and MK2Alessandro Annibaldi, Sidonie Wicky John, Tom Vanden Berghe, et al.
Nature Chemical Biology|May 17, 2016
A cascading activity-based probe sequentially targets E1-E2-E3 ubiquitin enzymesMonique P C Mulder, Katharina Witting, Ilana Berlin, et al.
The EMBO Journal|October 26, 2021
Oligomerization-driven MLKL ubiquitylation antagonizes necroptosisZikou Liu, Laura F Dagley, Kristy Shield-Artin, et al.
Biochimica Et Biophysica Acta. General Subjects|October 3, 2020
The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathwayValentine Spagnol, Caio A B Oliveira, Suzanne J Randle, et al.
Biorxiv : the Preprint Server for Biology|August 6, 2025
Differentiation of <i>Toxoplasma</i> into latent forms is linked to central carbon metabolism and requires a GID/CTLH-type E3 ubiquitin ligaseAlessandro D Uboldi, Sachin Khurana, Amalie A Jaywickrama, et al.
Nature|October 13, 2016
Molecular basis of Lys11-polyubiquitin specificity in the deubiquitinase CezanneTycho E T Mevissen, Yogesh Kulathu, Monique P C Mulder, et al.
Molecular and Cellular Biology|March 19, 2008
Mutation of the PDK1 PH domain inhibits protein kinase B/Akt, leading to small size and insulin resistanceJose R Bayascas, Stephan Wullschleger, Kei Sakamoto, et al.
Nature Communications|March 25, 2023
Neutron-encoded diubiquitins to profile linkage selectivity of deubiquitinating enzymesBianca D M van Tol, Bjorn R van Doodewaerd, Guinevere S M Lageveen-Kammeijer, et al.
EMBO Reports|July 11, 2024
PPTC7 antagonizes mitophagy by promoting BNIP3 and NIX degradation via SCF<sup>FBXL4</sup>Giang Thanh Nguyen-Dien, Brendan Townsend, Prajakta Gosavi Kulkarni, et al.
Pageof 15