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Cardiovascular Therapeutics|October 28, 2017
The effects of single- and multiple-dose administration of bococizumab (RN316/PF-04950615), a humanized IgG2Δa monoclonal antibody binding proprotein convertase subtilisin/kexin type 9, in hypercholesterolemic subjects treated with and without atorvastatin: Results from four phase I studiesBarry Gumbiner, Tenshang Joh, Hong Liang, et al.
Cancer Research|October 19, 2005
A blocking antibody to nerve growth factor attenuates skeletal pain induced by prostate tumor cells growing in boneKyle G Halvorson, Kazufumi Kubota, Molly A Sevcik, et al.
Oncotarget|October 17, 2018
RN765C, a low affinity EGFR antibody drug conjugate with potent anti-tumor activity in preclinical solid tumor modelsOi Kwan Wong, Thomas-Toan Tran, Wei-Hsien Ho, et al.
Annals of the Rheumatic Diseases|July 7, 2016
Nerve growth factor inhibition with tanezumab influences weight-bearing and subsequent cartilage damage in the rat medial meniscal tear modelTimothy P LaBranche, Alison M Bendele, Brian C Omura, et al.
Journal of the Peripheral Nervous System : JPNS|November 23, 2006
Artemin has potent neurotrophic actions on injured C-fibresDavid L H Bennett, Timothy J Boucher, Gregory J Michael, et al.
Pain|April 20, 2005
Anti-NGF therapy profoundly reduces bone cancer pain and the accompanying increase in markers of peripheral and central sensitizationMolly A Sevcik, Joseph R Ghilardi, Christopher M Peters, et al.
The Journal of Biological Chemistry|April 30, 2016
Engineering Highly Potent and Selective Microproteins against Nav1.7 Sodium Channel for Treatment of PainAnatoly Shcherbatko, Andrea Rossi, Davide Foletti, et al.
Scientific Reports|February 23, 2019
Optimal design, anti-tumour efficacy and tolerability of anti-CXCR4 antibody drug conjugatesMaria José Costa, Jyothirmayee Kudaravalli, Jing-Tyan Ma, et al.
The Journal of Pharmacology and Experimental Therapeutics|October 25, 2011
Proprotein convertase substilisin/kexin type 9 antagonism reduces low-density lipoprotein cholesterol in statin-treated hypercholesterolemic nonhuman primatesHong Liang, Javier Chaparro-Riggers, Pavel Strop, et al.
Molecular Cancer Therapeutics|March 6, 2016
Molecular Basis of Valine-Citrulline-PABC Linker Instability in Site-Specific ADCs and Its Mitigation by Linker DesignMagdalena Dorywalska, Russell Dushin, Ludivine Moine, et al.
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