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David M Burns

Showing results (51-60 of 60) with videos related to

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Nature Communications|March 18, 2022
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during agingAdelaida R Palla, Keren I Hilgendorf, Ann V Yang, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2022
Discovery of a novel 2-spiroproline steroid mimetic scaffold for the potent inhibition of 11β-HSD1David M Burns, Chunhong He, Yun-Long Li, et al.
Bioorganic & Medicinal Chemistry Letters|December 11, 2007
Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutationsDavid M Burns, Chunhong He, Yanlong Li, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2009
Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibitionDavid M Burns, Yun-Long Li, Eric Shi, et al.
Transplantation|October 26, 2020
Real-world Outcomes With Rituximab-based Therapy for Posttransplant Lymphoproliferative Disease Arising After Solid Organ TransplantDavid M Burns, Katherine Clesham, Yan A Hodgson, et al.
Cell Stem Cell|June 13, 2025
Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strengthYu Xin Wang, Adelaida R Palla, Andrew T V Ho, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2007
Design and identification of selective HER-2 sheddase inhibitors via P1' manipulation and unconventional P2' perturbations to induce a molecular metamorphosisWenqing Yao, Jincong Zhuo, David M Burns, et al.
Bioorganic & Medicinal Chemistry Letters|May 10, 2022
Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11β-HSD1 using a scaffold-hopping approachColin Zhang, Meizhong Xu, Chunhong He, et al.
Journal of Medicinal Chemistry|May 27, 2026
Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune DiseasesJincong Zhuo, Yun-Long Li, Ding-Quan Qian, et al.
Journal of Medicinal Chemistry|January 30, 2007
Discovery of a potent, selective, and orally active human epidermal growth factor receptor-2 sheddase inhibitor for the treatment of cancerWenqing Yao, Jincong Zhuo, David M Burns, et al.
Pageof 6

Showing results (51-60 of 60) with videos related to

Sort By:
Pageof 6
You have reached the last page of results.This site can display upto 60 results.
Nature Communications|March 18, 2022
Primary cilia on muscle stem cells are critical to maintain regenerative capacity and are lost during agingAdelaida R Palla, Keren I Hilgendorf, Ann V Yang, et al.
Bioorganic & Medicinal Chemistry Letters|July 14, 2022
Discovery of a novel 2-spiroproline steroid mimetic scaffold for the potent inhibition of 11β-HSD1David M Burns, Chunhong He, Yun-Long Li, et al.
Bioorganic & Medicinal Chemistry Letters|December 11, 2007
Conversion of an MMP-potent scaffold to an MMP-selective HER-2 sheddase inhibitor via scaffold hybridization and subtle P1' permutationsDavid M Burns, Chunhong He, Yanlong Li, et al.
Bioorganic & Medicinal Chemistry Letters|May 22, 2009
Compelling P1 substituent affect on metalloprotease binding profile enables the design of a novel cyclohexyl core scaffold with excellent MMP selectivity and HER-2 sheddase inhibitionDavid M Burns, Yun-Long Li, Eric Shi, et al.
Transplantation|October 26, 2020
Real-world Outcomes With Rituximab-based Therapy for Posttransplant Lymphoproliferative Disease Arising After Solid Organ TransplantDavid M Burns, Katherine Clesham, Yan A Hodgson, et al.
Cell Stem Cell|June 13, 2025
Multiomic profiling reveals that prostaglandin E2 reverses aged muscle stem cell dysfunction, leading to increased regeneration and strengthYu Xin Wang, Adelaida R Palla, Andrew T V Ho, et al.
Bioorganic & Medicinal Chemistry Letters|November 27, 2007
Design and identification of selective HER-2 sheddase inhibitors via P1' manipulation and unconventional P2' perturbations to induce a molecular metamorphosisWenqing Yao, Jincong Zhuo, David M Burns, et al.
Bioorganic & Medicinal Chemistry Letters|May 10, 2022
Discovery of 1'-(1-phenylcyclopropane-carbonyl)-3H-spiro[isobenzofuran-1,3'-pyrrolidin]-3-one as a novel steroid mimetic scaffold for the potent and tissue-specific inhibition of 11β-HSD1 using a scaffold-hopping approachColin Zhang, Meizhong Xu, Chunhong He, et al.
Journal of Medicinal Chemistry|May 27, 2026
Discovery of the Orally Bioavailable Isoform Selective Janus Kinase 1 (JAK1) Compound Povorcitinib (INCB054707) for the Treatment of Inflammatory and Autoimmune DiseasesJincong Zhuo, Yun-Long Li, Ding-Quan Qian, et al.
Journal of Medicinal Chemistry|January 30, 2007
Discovery of a potent, selective, and orally active human epidermal growth factor receptor-2 sheddase inhibitor for the treatment of cancerWenqing Yao, Jincong Zhuo, David M Burns, et al.
Pageof 6