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Current Opinion in Chemical Biology|August 2, 2005
Mechanisms of acetohydroxyacid synthasesDavid M Chipman, Ronald G Duggleby, Kai TittmannBiochemistry|July 9, 2004
Electron transfer in acetohydroxy acid synthase as a side reaction of catalysis. Implications for the reactivity and partitioning of the carbanion/enamine form of (alpha-hydroxyethyl)thiamin diphosphate in a "nonredox" flavoenzymeKai Tittmann, Kathrin Schröder, Ralph Golbik, et al.Biochemistry|July 2, 2003
NMR analysis of covalent intermediates in thiamin diphosphate enzymesKai Tittmann, Ralph Golbik, Kathrin Uhlemann, et al.Proceedings of the National Academy of Sciences of the United States of America|January 11, 2005
The carboligation reaction of acetohydroxyacid synthase II: steady-state intermediate distributions in wild type and mutants by NMRKai Tittmann, Maria Vyazmensky, Gerhard Hübner, et al.The FEBS Journal|March 27, 2012
Many of the functional differences between acetohydroxyacid synthase (AHAS) isozyme I and other AHASs are a result of the rapid formation and breakdown of the covalent acetolactate-thiamin diphosphate adduct in AHAS IInna Belenky, Andrea Steinmetz, Maria Vyazmensky, et al.Biochemistry|March 5, 2011
Significant catalytic roles for Glu47 and Gln 110 in all four of the C-C bond-making and -breaking steps of the reactions of acetohydroxyacid synthase IIMaria Vyazmensky, Andrea Steinmetz, Danilo Meyer, et al.Biochemistry|May 28, 2010
Valine 375 and phenylalanine 109 confer affinity and specificity for pyruvate as donor substrate in acetohydroxy acid synthase isozyme II from Escherichia coliAndrea Steinmetz, Maria Vyazmensky, Danilo Meyer, et al.Journal of Enzyme Inhibition and Medicinal Chemistry|May 24, 2007
Quantifying the inactivation rate constants for the molecular species comprising the catalytic cycle of Leuconostoc mesenteroides glucose 6-phosphate dehydrogenaseRonald G DugglebyAccounts of Chemical Research|August 16, 2006
Domain relationships in thiamine diphosphate-dependent enzymesRonald G DugglebyJournal of Enzyme Inhibition and Medicinal Chemistry|May 18, 2005
Suicide inhibition of acetohydroxyacid synthase by hydroxypyruvateRonald G DugglebyPageof 13