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David M Sabatini

Showing results (101-110 of 257) with videos related to

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Nature Communications|November 28, 2013
The TSC-mTOR pathway regulates macrophage polarizationVanessa Byles, Anthony J Covarrubias, Issam Ben-Sahra, et al.
Current Biology : CB|August 22, 2006
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2sMaria A Frias, Carson C Thoreen, Jacob D Jaffe, et al.
Science Advances|November 5, 2020
Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen speciesHyewon Kong, Colleen R Reczek, Gregory S McElroy, et al.
Iscience|May 18, 2020
A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human CellsG Jordan Ray, Elizabeth A Boydston, Emily Shortt, et al.
Molecular Cell|October 8, 2013
The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1Zhi-Yang Tsun, Liron Bar-Peled, Lynne Chantranupong, et al.
Science (New York, N.Y.)|October 10, 2015
Sestrin2 is a leucine sensor for the mTORC1 pathwayRachel L Wolfson, Lynne Chantranupong, Robert A Saxton, et al.
Journal of Medicinal Chemistry|February 17, 2011
Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancerQingsong Liu, Jinhua Wang, Seong A Kang, et al.
Cell|April 8, 2017
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP SynthaseJason R Cantor, Monther Abu-Remaileh, Naama Kanarek, et al.
Science (New York, N.Y.)|May 24, 2008
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 20, 2024
Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathwayMax L Valenstein, Pranav V Lalgudi, Xin Gu, et al.
Pageof 26

Showing results (101-110 of 257) with videos related to

Sort By:
Pageof 26
Nature Communications|November 28, 2013
The TSC-mTOR pathway regulates macrophage polarizationVanessa Byles, Anthony J Covarrubias, Issam Ben-Sahra, et al.
Current Biology : CB|August 22, 2006
mSin1 is necessary for Akt/PKB phosphorylation, and its isoforms define three distinct mTORC2sMaria A Frias, Carson C Thoreen, Jacob D Jaffe, et al.
Science Advances|November 5, 2020
Metabolic determinants of cellular fitness dependent on mitochondrial reactive oxygen speciesHyewon Kong, Colleen R Reczek, Gregory S McElroy, et al.
Iscience|May 18, 2020
A PEROXO-Tag Enables Rapid Isolation of Peroxisomes from Human CellsG Jordan Ray, Elizabeth A Boydston, Emily Shortt, et al.
Molecular Cell|October 8, 2013
The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1Zhi-Yang Tsun, Liron Bar-Peled, Lynne Chantranupong, et al.
Science (New York, N.Y.)|October 10, 2015
Sestrin2 is a leucine sensor for the mTORC1 pathwayRachel L Wolfson, Lynne Chantranupong, Robert A Saxton, et al.
Journal of Medicinal Chemistry|February 17, 2011
Discovery of 9-(6-aminopyridin-3-yl)-1-(3-(trifluoromethyl)phenyl)benzo[h][1,6]naphthyridin-2(1H)-one (Torin2) as a potent, selective, and orally available mammalian target of rapamycin (mTOR) inhibitor for treatment of cancerQingsong Liu, Jinhua Wang, Seong A Kang, et al.
Cell|April 8, 2017
Physiologic Medium Rewires Cellular Metabolism and Reveals Uric Acid as an Endogenous Inhibitor of UMP SynthaseJason R Cantor, Monther Abu-Remaileh, Naama Kanarek, et al.
Science (New York, N.Y.)|May 24, 2008
The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1Yasemin Sancak, Timothy R Peterson, Yoav D Shaul, et al.
Proceedings of the National Academy of Sciences of the United States of America|August 20, 2024
Rag-Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathwayMax L Valenstein, Pranav V Lalgudi, Xin Gu, et al.
Pageof 26