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Drug Discovery Today|June 23, 2021
Structural insights into understudied human cytochrome P450 enzymesDavid Machalz, Szymon Pach, Marcel Bermudez, et al.
Methods in Molecular Biology (Clifton, N.J.)|March 24, 2021
Exploiting Water Dynamics for Pharmacophore ScreeningDavid Schaller, Szymon Pach, Marcel Bermudez, et al.
RSC Medicinal Chemistry|June 7, 2021
A benzoxazole derivative as an inhibitor of anaerobic choline metabolism by human gut microbiotaMoustafa T Gabr, David Machalz, Szymon Pach, et al.
FEBS Letters|June 15, 2019
Functional characterization and mechanistic modeling of the human cytochrome P450 enzyme CYP4A22Pradeepraj Durairaj, Linbing Fan, David Machalz, et al.
Biomolecules|November 11, 2020
Functional Expression of All Human Sulfotransferases in Fission Yeast, Assay Development, and Structural Models for Isoforms SULT4A1 and SULT6B1Yanan Sun, David Machalz, Gerhard Wolber, et al.
Applied Biochemistry and Biotechnology|September 2, 2020
New Proluciferin Substrates for Human CYP4 Family EnzymesJingyao Liu, David Machalz, Gerhard Wolber, et al.
Molecular Vision|December 9, 2021
A convenient test system for the identification of CYP4V2 inhibitorsShishir Sharma, Sijie Liu, Pradeepraj Durairaj, et al.
FEBS Letters|May 1, 2018
A common polymorphic variant of UGT1A5 displays increased activity due to optimized cofactor bindingFan Yang, David Machalz, Sisi Wang, et al.
Biochemical Pharmacology|February 12, 2020
Importance of asparagine-381 and arginine-487 for substrate recognition in CYP4Z1Wei Du, David Machalz, Qi Yan, et al.
Biochemical Pharmacology|September 28, 2017
Efficient substrate screening and inhibitor testing of human CYP4Z1 using permeabilized recombinant fission yeastQi Yan, David Machalz, Andy Zöllner, et al.
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