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Biorxiv : the Preprint Server for Biology|February 22, 2023
Extracellular communication between brain cells through functional transfer of Cre mRNADavid Rufino-Ramos, Kevin Leandro, Pedro R L Perdigão, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|November 20, 2024
CRISPR targeting of mmu-miR-21a through a single adeno-associated virus vector prolongs survival of glioblastoma-bearing miceLisa Nieland, Anne B Vrijmoet, Isabelle W Jetten, et al.Nature Biotechnology|July 22, 2024
Click editing enables programmable genome writing using DNA polymerases and HUH endonucleasesJoana Ferreira da Silva, Connor J Tou, Emily M King, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|April 7, 2023
Extracellular vesicle-based delivery of silencing sequences for the treatment of Machado-Joseph disease/spinocerebellar ataxia type 3David Rufino-Ramos, Patrícia R Albuquerque, Kevin Leandro, et al.Molecular Therapy. Nucleic Acids|March 21, 2025
Non-invasive detection of allele-specific CRISPR-SaCas9-KKH disruption of TOR1A DYT1 allele in a xenograft mouse modelKatia E Maalouf, Dawn Madison Frederick, Nutan Sharma, et al.Journal of Extracellular Vesicles|June 17, 2025
Engineering of CD63 Enables Selective Extracellular Vesicle Cargo Loading and Enhanced Payload DeliveryWataru Obuchi, Ayrton Zargani-Piccardi, Kevin Leandro, et al.Biomaterials|March 14, 2026
Extracellular vesicles-mediated delivery of SpCas9 RNPs for therapeutic gene editing in Spinocerebellar Ataxia Type 3Kevin Leandro, David Rufino-Ramos, Sara M Lopes, et al.Nature|March 12, 2026
Immune evasive DNA donors and recombinases license kilobase-scale writingConnor J Tou, Keqiang Xie, Joana Ferreira da Silva, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|October 13, 2025
Extracellular vesicles-associated AAVs for the treatment of Machado-Joseph diseaseCarina Henriques, Patrícia Albuquerque, David Rufino-Ramos, et al.Molecular Therapy : the Journal of the American Society of Gene Therapy|August 22, 2025
Intratumoral delivery of 4-1BBL boosts IL-12-triggered anti-glioma immunityTaral R Lunavat, Lisa Nieland, Sanne M van de Looij, et al.Pageof 3