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Toxicological Sciences : an Official Journal of the Society of Toxicology|June 1, 2022
Recovered Hepatocytes Promote Macrophage Apoptosis Through CXCR4 After Acetaminophen-Induced Liver Injury in MiceNga T Nguyen, David S Umbaugh, Eileen L Huang, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology|October 15, 2025
The endothelial growth factor angiopoietin-2 is an accurate prognostic biomarker in patients with acetaminophen-induced acute liver failureDavid S Umbaugh, Nga T Nguyen, Steven C Curry, et al.
Hepatology (Baltimore, Md.)|November 1, 2023
The chemokine CXCL14 is a novel early prognostic biomarker for poor outcome in acetaminophen-induced acute liver failureDavid S Umbaugh, Nga T Nguyen, Steven C Curry, et al.
Acta Pharmaceutica Sinica. B|January 13, 2022
Recommendations for the use of the acetaminophen hepatotoxicity model for mechanistic studies and how to avoid common pitfallsHartmut Jaeschke, Olamide B Adelusi, Jephte Y Akakpo, et al.
Hepatology (Baltimore, Md.)|February 2, 2026
Age and sex influence transcriptomic responses to statin therapy that control liver aging during systemic metabolic dysfunctionDavid S Umbaugh, Liuyang Wang, Kuo Du, et al.
Gut|January 14, 2026
Zinc-dependent RNA-binding protein controls hepatocyte senescence and recovery from alcohol-related liver failureRajesh Kumar Dutta, Kuo Du, Niansheng Ren, et al.
Biorxiv : the Preprint Server for Biology|June 29, 2026
Disrupted Mitochondrial Copper Homeostasis Promotes Ferroptotic Stress, Senescence and MASLD ProgressionNiansheng Ren, Liuyang Wang, Rajesh K Dutta, et al.
Archives of Toxicology|September 4, 2022
Human Wharton's Jelly-derived mesenchymal stem cells prevent acetaminophen-induced liver injury in a mouse model unlike human dermal fibroblastsDavid S Umbaugh, Rupal P Soder, Nga T Nguyen, et al.
JCI Insight|May 19, 2026
Hepatocyte hedgehog signaling controls ferroptosis to alleviate aging-related organ dysfunctionJi Hye Jun, Rajesh K Dutta, Soon-Woo Cho, et al.
Cellular and Molecular Gastroenterology and Hepatology|January 30, 2022
Regulation of Liver Regeneration by Hepatocyte O-GlcNAcylation in MiceDakota R Robarts, Steven R McGreal, David S Umbaugh, et al.
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