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David W Piotrowski

Showing results (11-20 of 43) with videos related to

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Plos One|November 15, 2018
Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugsHao Sun, David W Piotrowski, Suvi T M Orr, et al.
Journal of Translational Medicine|October 25, 2011
The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonismRena J Eudy, Vaishali Sahasrabudhe, Kevin Sweeney, et al.
Bioorganic & Medicinal Chemistry Letters|November 29, 2018
Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9Allyn T Londregan, Gary Aspnes, Chris Limberakis, et al.
Bioorganic & Medicinal Chemistry Letters|January 23, 2013
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial librariesAllyn T Londregan, David W Piotrowski, Kentaro Futatsugi, et al.
Angewandte Chemie (International Ed. in English)|April 15, 2020
Cycloisomerization of Olefins in WaterJeishla L M Matos, Samantha A Green, Yuge Chun, et al.
American Journal of Hematology|April 23, 2021
PF-07059013: A non-covalent hemoglobin modulator favorably impacts disease state in a mouse model of sickle cell diseaseKelly M Knee, Reema Jasuja, Amey Barakat, et al.
Chemical Science|June 7, 2021
Merging C(sp<sup>3</sup>)-H activation with DNA-encodingZhoulong Fan, Shuai Zhao, Tao Liu, et al.
Journal of Medicinal Chemistry|January 5, 2018
Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid AntagonistsDavid W Piotrowski, Kentaro Futatsugi, Agustin Casimiro-Garcia, et al.
Bioorganic & Medicinal Chemistry Letters|February 18, 2011
N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitorsKaren A Atkinson, Elena E Beretta, Janice A Brown, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|April 29, 2005
A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterizationRaymond S Hurst, Mihaly Hajós, Mario Raggenbass, et al.
Pageof 5

Showing results (11-20 of 43) with videos related to

Sort By:
Pageof 5
Plos One|November 15, 2018
Deuterium isotope effects in drug pharmacokinetics II: Substrate-dependence of the reaction mechanism influences outcome for cytochrome P450 cleared drugsHao Sun, David W Piotrowski, Suvi T M Orr, et al.
Journal of Translational Medicine|October 25, 2011
The use of plasma aldosterone and urinary sodium to potassium ratio as translatable quantitative biomarkers of mineralocorticoid receptor antagonismRena J Eudy, Vaishali Sahasrabudhe, Kevin Sweeney, et al.
Bioorganic & Medicinal Chemistry Letters|November 29, 2018
Discovery of N-(piperidin-3-yl)-N-(pyridin-2-yl)piperidine/piperazine-1-carboxamides as small molecule inhibitors of PCSK9Allyn T Londregan, Gary Aspnes, Chris Limberakis, et al.
Bioorganic & Medicinal Chemistry Letters|January 23, 2013
Discovery of 5-phenoxy-1,3-dimethyl-1H-pyrazole-4-carboxamides as potent agonists of TGR5 via sequential combinatorial librariesAllyn T Londregan, David W Piotrowski, Kentaro Futatsugi, et al.
Angewandte Chemie (International Ed. in English)|April 15, 2020
Cycloisomerization of Olefins in WaterJeishla L M Matos, Samantha A Green, Yuge Chun, et al.
American Journal of Hematology|April 23, 2021
PF-07059013: A non-covalent hemoglobin modulator favorably impacts disease state in a mouse model of sickle cell diseaseKelly M Knee, Reema Jasuja, Amey Barakat, et al.
Chemical Science|June 7, 2021
Merging C(sp<sup>3</sup>)-H activation with DNA-encodingZhoulong Fan, Shuai Zhao, Tao Liu, et al.
Journal of Medicinal Chemistry|January 5, 2018
Identification of Morpholino-2H-pyrido[3,2-b][1,4]oxazin-3(4H)-ones as Nonsteroidal Mineralocorticoid AntagonistsDavid W Piotrowski, Kentaro Futatsugi, Agustin Casimiro-Garcia, et al.
Bioorganic & Medicinal Chemistry Letters|February 18, 2011
N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitorsKaren A Atkinson, Elena E Beretta, Janice A Brown, et al.
The Journal of Neuroscience : the Official Journal of the Society for Neuroscience|April 29, 2005
A novel positive allosteric modulator of the alpha7 neuronal nicotinic acetylcholine receptor: in vitro and in vivo characterizationRaymond S Hurst, Mihaly Hajós, Mario Raggenbass, et al.
Pageof 5