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David Weaver

Showing results (151-160 of 173) with videos related to

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Molecular Pharmacology|October 25, 2011
Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system functionMeredith J Noetzel, Jerri M Rook, Paige N Vinson, et al.
Biorxiv : the Preprint Server for Biology|May 18, 2026
Fatty Acid Oxidation Suppression Reprograms Fibroblasts in Fibrostenotic Crohn's DiseaseJihad Aljabban, Ayesh Awad, Benjamin D McMichael, et al.
Human Mutation|May 26, 2017
Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxiaAlessia Nasca, Chiara Scotton, Irina Zaharieva, et al.
Bioorganic & Medicinal Chemistry Letters|November 13, 2012
Discovery and SAR of a novel series of non-MPEP site mGlu₅ PAMs based on an aryl glycine sulfonamide scaffoldAlice L Rodriguez, Ya Zhou, Richard Williams, et al.
Blood|December 14, 2017
Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphomaSteven M Horwitz, Raphael Koch, Pierluigi Porcu, et al.
Current Topics in Medicinal Chemistry|October 8, 2009
Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probeC David Weaver, Douglas J Sheffler, L Michelle Lewis, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2004
Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1H-indol-5-yl)-ethyl acrylamidesYong-Jin Wu, Li-Qiang Sun, Huan He, et al.
Molecular Pharmacology|December 3, 2008
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activityJoy E Marlo, Colleen M Niswender, Emily L Days, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 17, 2023
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm functionMaximilian Lyon, Ping Li, Juan J Ferreira, et al.
Journal of Medicinal Chemistry|October 5, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)) with oral efficacy in an antiparkinsonian animal modelCarrie K Jones, Darren W Engers, Analisa D Thompson, et al.
Pageof 18

Showing results (151-160 of 173) with videos related to

Sort By:
Pageof 18
Molecular Pharmacology|October 25, 2011
Functional impact of allosteric agonist activity of selective positive allosteric modulators of metabotropic glutamate receptor subtype 5 in regulating central nervous system functionMeredith J Noetzel, Jerri M Rook, Paige N Vinson, et al.
Biorxiv : the Preprint Server for Biology|May 18, 2026
Fatty Acid Oxidation Suppression Reprograms Fibroblasts in Fibrostenotic Crohn's DiseaseJihad Aljabban, Ayesh Awad, Benjamin D McMichael, et al.
Human Mutation|May 26, 2017
Recessive mutations in MSTO1 cause mitochondrial dynamics impairment, leading to myopathy and ataxiaAlessia Nasca, Chiara Scotton, Irina Zaharieva, et al.
Bioorganic & Medicinal Chemistry Letters|November 13, 2012
Discovery and SAR of a novel series of non-MPEP site mGlu₅ PAMs based on an aryl glycine sulfonamide scaffoldAlice L Rodriguez, Ya Zhou, Richard Williams, et al.
Blood|December 14, 2017
Activity of the PI3K-δ,γ inhibitor duvelisib in a phase 1 trial and preclinical models of T-cell lymphomaSteven M Horwitz, Raphael Koch, Pierluigi Porcu, et al.
Current Topics in Medicinal Chemistry|October 8, 2009
Discovery and development of a potent and highly selective small molecule muscarinic acetylcholine receptor subtype I (mAChR 1 or M1) antagonist in vitro and in vivo probeC David Weaver, Douglas J Sheffler, L Michelle Lewis, et al.
Bioorganic & Medicinal Chemistry Letters|September 11, 2004
Synthesis and KCNQ2 opener activity of N-(1-benzo[1,3]dioxol-5-yl-ethyl, N-[1-(2,3-dihydro-benzofuran-5-yl)-ethyl, and N-[1-(2,3-dihydro-1H-indol-5-yl)-ethyl acrylamidesYong-Jin Wu, Li-Qiang Sun, Huan He, et al.
Molecular Pharmacology|December 3, 2008
Discovery and characterization of novel allosteric potentiators of M1 muscarinic receptors reveals multiple modes of activityJoy E Marlo, Colleen M Niswender, Emily L Days, et al.
Proceedings of the National Academy of Sciences of the United States of America|January 17, 2023
A selective inhibitor of the sperm-specific potassium channel SLO3 impairs human sperm functionMaximilian Lyon, Ping Li, Juan J Ferreira, et al.
Journal of Medicinal Chemistry|October 5, 2011
Discovery, synthesis, and structure-activity relationship development of a series of N-4-(2,5-dioxopyrrolidin-1-yl)phenylpicolinamides (VU0400195, ML182): characterization of a novel positive allosteric modulator of the metabotropic glutamate receptor 4 (mGlu(4)) with oral efficacy in an antiparkinsonian animal modelCarrie K Jones, Darren W Engers, Analisa D Thompson, et al.
Pageof 18