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Reproductive Toxicology (Elmsford, N.Y.)|March 24, 2010
Testis dysfunction by isoproterenol is mediated by upregulating endothelin receptor A, leptin and protein kinase Cvarepsilon and is attenuated by an endothelin receptor antagonist CPU0213Yu-Si Cheng, De-Zai Dai, Yin DaiThe Journal of Pharmacy and Pharmacology|May 2, 2009
Stress-induced cardiac insufficiency relating to abnormal leptin and FKBP12.6 is ameliorated by CPU0213, an endothelin receptor antagonist, which is not affected by the CYP3A suppressing effect of erythromycinYu-Si Cheng, De-Zai Dai, Yin DaiActa Pharmacologica Sinica|July 15, 2009
Isoproterenol disperses distribution of NADPH oxidase, MMP-9, and pPKCepsilon in the heart, which are mitigated by endothelin receptor antagonist CPU0213Yu-si Cheng, De-zai Dai, Yin DaiThe Journal of Pharmacy and Pharmacology|July 9, 2010
NaHS ameliorates diabetic vascular injury by correcting depressed connexin 43 and 40 in the vasculature in streptozotocin-injected ratsYu-Fen Zheng, De-Zai Dai, Yin DaiLife Sciences|July 11, 2006
Up-regulated inflammatory factors endothelin, NFkappaB, TNFalpha and iNOS involved in exaggerated cardiac arrhythmias in l-thyroxine-induced cardiomyopathy are suppressed by darusentan in ratsHui-Jing Xia, De-Zai Dai, Yin DaiActa Pharmacologica Sinica|February 11, 2004
Downregulation of Kv4.2 and Kv4.3 channel gene expression in right ventricular hypertrophy induced by monocrotaline in ratTian-tai Zhang, Bing Cui, De-zai DaiActa Pharmacologica Sinica|August 23, 2006
CPU0213, a novel endothelin receptor antagonist, ameliorates septic renal lesion by suppressing ET system and NF-kappaB in ratsHai-bo He, De-zai Dai, Yin DaiActa Pharmacologica Sinica|February 24, 2006
Pharmacokinetics of CPU0213, a novel endothelin receptor antagonist, after intravenous administration in miceLi Guan, Yu Feng, Min Ji, et al.European Journal of Pharmacology|July 10, 2008
Endothelin receptor antagonist CPU0213 and vitamin E reverse downregulation of FKBP12.6 and SERCA2a: a role of hyperphosphorylation of PKCepsilonNa Li, Nan Jia, De-Zai Dai, et al.Acta Pharmacologica Sinica|October 18, 2005
CPU 86017, p-chlorobenzyltetrahydroberberine chloride, attenuates monocrotaline-induced pulmonary hypertension by suppressing endothelin pathwayTian-tai Zhang, Bing Cui, De-zai Dai, et al.Pageof 8