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Bioorganic & Medicinal Chemistry Letters|August 20, 2010
SAR development of a series of 8-azabicyclo[3.2.1]octan-3-yloxy-benzamides as kappa opioid receptor antagonists. Part 2Todd A Brugel, Reed W Smith, Michael Balestra, et al.Bioorganic & Medicinal Chemistry Letters|November 12, 2013
Discovery of a potent respiratory syncytial virus RNA polymerase inhibitorHui Xiong, Melinda Foulk, Lisa Aschenbrenner, et al.Bioorganic & Medicinal Chemistry Letters|February 8, 2011
Discovery of novel positive allosteric modulators of the metabotropic glutamate receptor 5 (mGlu5)Jeffrey G Varnes, Andrew P Marcus, Russell C Mauger, et al.Cell Death Discovery|March 4, 2020
Phenotypic high-throughput screening platform identifies novel chemotypes for necroptosis inhibitionHugo Brito, Vanda Marques, Marta B Afonso, et al.Journal of Bacteriology|March 4, 2015
Novel antibacterial targets and compounds revealed by a high-throughput cell wall reporter assayAsha S Nayar, Thomas J Dougherty, Keith E Ferguson, et al.ACS Chemical Neuroscience|November 4, 2015
Discovery and Preclinical Validation of [(11)C]AZ13153556, a Novel Probe for the Histamine Type 3 ReceptorMagnus Schou, Katarina Varnäs, Anders Jureus, et al.Nature Reviews. Drug Discovery|January 20, 2018
Impact of a five-dimensional framework on R&D productivity at AstraZenecaPaul Morgan, Dean G Brown, Simon Lennard, et al.Communications Biology|December 18, 2020
Protease-activated receptor-2 ligands reveal orthosteric and allosteric mechanisms of receptor inhibitionAmanda J Kennedy, Linda Sundström, Stefan Geschwindner, et al.Bioorganic & Medicinal Chemistry Letters|September 25, 2003
Synthesis of 7-chloro-2,3-dihydro-2-[1-(pyridinyl)alkyl]-pyridazino[4,5-b]quinoline-1,4,10(5H)-triones as NMDA glycine-site antagonistsDean G Brown, Rebecca A Urbanek, Thomas M Bare, et al.Bioorganic & Medicinal Chemistry Letters|June 3, 2019
Tool inhibitors and assays to interrogate the biology of the TRAF2 and NCK interacting kinaseJon Read, Iain T Collie, Michelle Nguyen-McCarty, et al.Pageof 6