Showing results (11-20 of 28) with videos related to

Sort By:
Pageof 3
Plos One|July 18, 2013
Label free fragment screening using surface plasmon resonance as a tool for fragment finding - analyzing parkin, a difficult CNS targetKarin Regnström, Jiangli Yan, Lan Nguyen, et al.
Bioorganic & Medicinal Chemistry Letters|April 11, 2013
Design and synthesis of thiophene dihydroisoquinolines as novel BACE1 inhibitorsYing-Zi Xu, Shendong Yuan, Simeon Bowers, et al.
The Journal of Biological Chemistry|January 6, 2005
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivoAlan G Olivero, Charles Eigenbrot, Richard Goldsmith, et al.
Bioorganic & Medicinal Chemistry Letters|March 8, 2013
Structure-based design of novel dihydroisoquinoline BACE-1 inhibitors that do not engage the catalytic aspartatesSimeon Bowers, Ying-zi Xu, Shendong Yuan, et al.
Elife|April 9, 2025
High-resolution deep mutational scanning of the melanocortin-4 receptor enables target characterization for drug discoveryConor J Howard, Nathan S Abell, Beatriz A Osuna, et al.
Bioorganic & Medicinal Chemistry Letters|November 13, 2010
Design and synthesis of disubstituted thiophene and thiazole based inhibitors of JNKRoy K Hom, Simeon Bowers, Jennifer M Sealy, et al.
Bioorganic & Medicinal Chemistry Letters|February 15, 2011
Design and synthesis of a novel, orally active, brain penetrant, tri-substituted thiophene based JNK inhibitorSimeon Bowers, Anh P Truong, R Jeffrey Neitz, et al.
Proceedings of the National Academy of Sciences of the United States of America|March 16, 2013
Design and pharmacology of a highly specific dual FMS and KIT kinase inhibitorChao Zhang, Prabha N Ibrahim, Jiazhong Zhang, et al.
Bioorganic & Medicinal Chemistry Letters|July 17, 2010
Improving the permeability of the hydroxyethylamine BACE-1 inhibitors: structure-activity relationship of P2' substituentsAnh P Truong, Gary D Probst, Jose Aquino, et al.
Bioorganic & Medicinal Chemistry Letters|July 17, 2013
Design and synthesis of hydroxyethylamine (HEA) BACE-1 inhibitors: prime side chromane-containing inhibitorsRaymond A Ng, Minghua Sun, Simeon Bowers, et al.
Pageof 3