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Bioorganic & Medicinal Chemistry Letters|May 3, 2015
Boronic acid-containing CXCR1/2 antagonists: Optimization of metabolic stability, in vivo evaluation, and a proposed receptor binding modelDean Y Maeda, Angela M Peck, Aaron D Schuler, et al.Bioorganic & Medicinal Chemistry Letters|August 8, 2015
Boronic acid-containing aminopyridine- and aminopyrimidinecarboxamide CXCR1/2 antagonists: Optimization of aqueous solubility and oral bioavailabilityAaron D Schuler, Courtney A Engles, Dean Y Maeda, et al.The Journal of Pharmacology and Experimental Therapeutics|June 2, 2012
Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporterAlan Menter, Breck Thrash, Christina Cherian, et al.American Journal of Physiology. Lung Cellular and Molecular Physiology|July 4, 2009
IL-8 signaling does not mediate intra-amniotic LPS-induced inflammation and maturation in preterm fetal lamb lungSuhas G Kallapur, Timothy J M Moss, Richard L Auten, et al.Nature Communications|August 19, 2021
Single-cell evaluation reveals shifts in the tumor-immune niches that shape and maintain aggressive lesions in the breastVidya C Sinha, Amanda L Rinkenbaugh, Mingchu Xu, et al.Journal for Immunotherapy of Cancer|March 20, 2020
Simultaneous inhibition of CXCR1/2, TGF-β, and PD-L1 remodels the tumor and its microenvironment to drive antitumor immunityLucas A Horn, Jeffrey Riskin, Heidi A Hempel, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|December 19, 2019
Inhibition of MDSC Trafficking with SX-682, a CXCR1/2 Inhibitor, Enhances NK-Cell Immunotherapy in Head and Neck Cancer ModelsSarah Greene, Yvette Robbins, Wojciech K Mydlarz, et al.Nature|March 22, 2017
Effective combinatorial immunotherapy for castration-resistant prostate cancerXin Lu, James W Horner, Erin Paul, et al.Journal of Experimental & Clinical Cancer Research : CR|December 5, 2024
Inhibition of the chemokine receptors CXCR1 and CXCR2 synergizes with docetaxel for effective tumor control and remodeling of the immune microenvironment of HPV-negative head and neck cancer modelsLucas A Horn, Hanne Lind, Kristen Fousek, et al.Cancer Discovery|August 6, 2021
Combined Inhibition of SHP2 and CXCR1/2 Promotes Antitumor T-cell Response in NSCLCKwan Ho Tang, Shuai Li, Alireza Khodadadi-Jamayran, et al.Pageof 3