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The Journal of Biological Chemistry|September 15, 2007
Dynamic regulation, desensitization, and cross-talk in discrete subcellular microdomains during beta2-adrenoceptor and prostanoid receptor cAMP signalingDebbie Willoughby, George S Baillie, Martin J Lynch, et al.
The Biochemical Journal|August 19, 2014
TRPC1 contributes to the Ca2+-dependent regulation of adenylate cyclasesDebbie Willoughby, Hwei Ling Ong, Lorena Brito De Souza, et al.
Journal of Cell Science|September 15, 2012
A key phosphorylation site in AC8 mediates regulation of Ca(2+)-dependent cAMP dynamics by an AC8-AKAP79-PKA signalling complexDebbie Willoughby, Michelle L Halls, Katy L Everett, et al.
The Journal of Biological Chemistry|April 23, 2010
AKAP79/150 interacts with AC8 and regulates Ca2+-dependent cAMP synthesis in pancreatic and neuronal systemsDebbie Willoughby, Nanako Masada, Sebastian Wachten, et al.
The Journal of Biological Chemistry|July 21, 2011
Palmitoylation targets AKAP79 protein to lipid rafts and promotes its regulation of calcium-sensitive adenylyl cyclase type 8Ilse Delint-Ramirez, Debbie Willoughby, Gerald R V Hammond, et al.
Science Signaling|April 13, 2012
Direct binding between Orai1 and AC8 mediates dynamic interplay between Ca2+ and cAMP signalingDebbie Willoughby, Katy L Everett, Michelle L Halls, et al.
Molecular Pharmacology|January 28, 2009
Capacitative Ca2+ entry via Orai1 and stromal interacting molecule 1 (STIM1) regulates adenylyl cyclase type 8Agnes C L Martin, Debbie Willoughby, Antonio Ciruela, et al.
Molecular Cell|September 16, 2006
Dynamic regulation of cAMP synthesis through anchored PKA-adenylyl cyclase V/VI complexesAndrea L Bauman, Joseph Soughayer, Bao T Nguyen, et al.
The Journal of Biological Chemistry|December 24, 2010
Small molecule AKAP-protein kinase A (PKA) interaction disruptors that activate PKA interfere with compartmentalized cAMP signaling in cardiac myocytesFrank Christian, Márta Szaszák, Sabine Friedl, et al.
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