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Gene Expression Patterns : GEP|June 9, 2005
eXPRESSION: an in silico tool to predict patterns of gene expressionDeborah A Ferguson, Jing-Tzyh Alan Chiang, James A Richardson, et al.
Journal of Biochemical and Molecular Toxicology|May 16, 2020
Omaveloxolone and TX63682 are hepatoprotective in the STAM mouse model of nonalcoholic steatohepatitisScott A Reisman, Deborah A Ferguson, Chun-Yue I Lee, et al.
Plos One|August 25, 2015
Cancer Cell Growth Is Differentially Affected by Constitutive Activation of NRF2 by KEAP1 Deletion and Pharmacological Activation of NRF2 by the Synthetic Triterpenoid, RTA 405Brandon L Probst, Lyndsey McCauley, Isaac Trevino, et al.
Bioorganic & Medicinal Chemistry Letters|July 29, 2008
Evaluating the potential of vacuolar ATPase inhibitors as anticancer agents and multigram synthesis of the potent salicylihalamide analog saliphenylhalamideSylvain Lebreton, Janis Jaunbergs, Michael G Roth, et al.
Plos One|April 22, 2015
RTA 408, A Novel Synthetic Triterpenoid with Broad Anticancer and Anti-Inflammatory ActivityBrandon L Probst, Isaac Trevino, Lyndsey McCauley, et al.
American Journal of Nephrology|April 22, 2011
Effect of bardoxolone methyl on kidney function in patients with T2D and Stage 3b-4 CKDPablo E Pergola, Melissa Krauth, J Warren Huff, et al.
Kidney International|December 14, 2012
The synthetic triterpenoid, RTA 405, increases the glomerular filtration rate and reduces angiotensin II-induced contraction of glomerular mesangial cellsYanfeng Ding, Rhesa D Stidham, Ron Bumeister, et al.
Biochimica Et Biophysica Acta|August 1, 2016
Characterization of novel small-molecule NRF2 activators: Structural and biochemical validation of stereospecific KEAP1 bindingCarlos Huerta, Xin Jiang, Isaac Trevino, et al.
Bioorganic & Medicinal Chemistry Letters|February 2, 2020
A novel series of cysteine-dependent, allosteric inverse agonists of the nuclear receptor RORγtXin Jiang, Irina Dulubova, Scott A Reisman, et al.
Clinical and Translational Science|August 30, 2020
Effects of Bardoxolone Methyl on Hepatic Enzymes in Patients with Type 2 Diabetes Mellitus and Stage 4 CKDJames H Lewis, Michel Jadoul, Geoffrey A Block, et al.
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