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The Journal of Pharmacology and Experimental Therapeutics|April 22, 2011
The metabotropic glutamate receptor 7 allosteric modulator AMN082: a monoaminergic agent in disguise?Stacey J Sukoff Rizzo, Sarah K Leonard, Adam Gilbert, et al.The Journal of Pharmacology and Experimental Therapeutics|January 10, 2008
Correlating efficacy in rodent cognition models with in vivo 5-hydroxytryptamine1a receptor occupancy by a novel antagonist, (R)-N-(2-methyl-(4-indolyl-1-piperazinyl)ethyl)-N-(2-pyridinyl)-cyclohexane carboxamide (WAY-101405)Warren D Hirst, Terrance H Andree, Suzan Aschmies, et al.Journal of Medicinal Chemistry|January 8, 2014
Discovery and preclinical characterization of 1-methyl-3-(4-methylpyridin-3-yl)-6-(pyridin-2-ylmethoxy)-1H-pyrazolo-[3,4-b]pyrazine (PF470): a highly potent, selective, and efficacious metabotropic glutamate receptor 5 (mGluR5) negative allosteric modulatorLei Zhang, Gayatri Balan, Gabriela Barreiro, et al.Journal of Medicinal Chemistry|August 18, 2017
Discovery and Characterization of (R)-6-Neopentyl-2-(pyridin-2-ylmethoxy)-6,7-dihydropyrimido[2,1-c][1,4]oxazin-4(9H)-one (PF-06462894), an Alkyne-Lacking Metabotropic Glutamate Receptor 5 Negative Allosteric Modulator Profiled in both Rat and Nonhuman PrimatesAntonia F Stepan, Michelle M Claffey, Matthew R Reese, et al.Pageof 5