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The Journal of Pharmacology and Experimental Therapeutics|January 27, 2009
A novel, highly selective, tight binding IkappaB kinase-2 (IKK-2) inhibitor: a tool to correlate IKK-2 activity to the fate and functions of the components of the nuclear factor-kappaB pathway in arthritis-relevant cells and animal modelsGabriel Mbalaviele, Cynthia D Sommers, Sheri L Bonar, et al.
International Immunopharmacology|July 9, 2010
Critical role for apoptosis signal-regulating kinase 1 in the development of inflammatory K/BxN serum-induced arthritisStephen J Mnich, Patrick M Blanner, Liangbiao G Hu, et al.
Science Advances|February 1, 2021
Inhibition of the NLRP3 inflammasome prevents ovarian agingJosé M Navarro-Pando, Elísabet Alcocer-Gómez, Beatriz Castejón-Vega, et al.
Blood|June 8, 2022
IL-1β expression in bone marrow dendritic cells is induced by TLR2 agonists and regulates HSC functionSidan Li, Juo-Chin Yao, Karolyn A Oetjen, et al.
Plos One|May 5, 2012
Constitutively activated NLRP3 inflammasome causes inflammation and abnormal skeletal development in miceSheri L Bonar, Susannah D Brydges, James L Mueller, et al.
The Journal of Biological Chemistry|February 20, 2010
Novel insights into the cellular mechanisms of the anti-inflammatory effects of NF-kappaB essential modulator binding domain peptidesEric T Baima, Julia A Guzova, Sumathy Mathialagan, et al.
FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology|December 6, 2014
NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanismsChao Qu, Sheri L Bonar, Cynthia L Hickman-Brecks, et al.
The Journal of Experimental Medicine|March 18, 2018
Selective inhibition of the p38α MAPK-MK2 axis inhibits inflammatory cues including inflammasome priming signalsChun Wang, Susan Hockerman, E Jon Jacobsen, et al.
Cancer Research|August 11, 2018
Inhibition of the Stromal p38MAPK/MK2 Pathway Limits Breast Cancer Metastases and Chemotherapy-Induced Bone LossBhavna Murali, Qihao Ren, Xianmin Luo, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 2, 2009
Anti-inflammatory properties of a novel N-phenyl pyridinone inhibitor of p38 mitogen-activated protein kinase: preclinical-to-clinical translationHeidi R Hope, Gary D Anderson, Barry L Burnette, et al.
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