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Critical Care Medicine|August 15, 2024
Digital Twins of Acute Hypoxemic Respiratory Failure Patients Suggest a Mechanistic Basis for Success and Failure of Noninvasive VentilationLiam Weaver, Hossein Shamohammadi, Sina Saffaran, et al.ACS Synthetic Biology|May 29, 2025
Gene Expression Depends on the Interplay Among Growth, Resource Biogenesis, and Nutrient QualityJuhyun Kim, Alexander P S Darlington, Said Muñoz-Montero, et al.IEEE Open Journal of Engineering in Medicine and Biology|August 26, 2024
Computational Simulation of Virtual Patients Reduces Dataset Bias and Improves Machine Learning-Based Detection of ARDS from Noisy Heterogeneous ICU DatasetsKonstantin Sharafutdinov, Sebastian Johannes Fritsch, Mina Iravani, et al.Critical Care (London, England)|March 7, 2025
Machine learning models compared with current clinical indices to predict the outcome of high flow nasal cannula therapy in acute hypoxemic respiratory failureHang Yu, Sina Saffaran, Roberto Tonelli, et al.Critical Care (London, England)|November 22, 2025
Evaluating the effect of heart and respiratory rate measurement errors on the ability to predict the outcome of high flow nasal cannula therapy: a multi-centre studyHang Yu, Sina Saffaran, Roberto Tonelli, et al.Anesthesiology|November 17, 2025
Individualized Flow-Controlled versus Pressure-Controlled Ventilation in Cardiac Surgery: A Randomized Controlled TrialSimon Becker, Christian T Kurz, Romina Schnitzler, et al.Critical Care Medicine|September 24, 2025
Digital Twins to Evaluate the Risk of Ventilator-Induced Lung Injury During Airway Pressure Release Ventilation Compared With Pressure-Controlled VentilationWilliam Joy, Beatrice Albanese, Diallo Oakley, et al.BMC Systems Biology|September 17, 2011
Computational modelling elucidates the mechanism of ciliary regulation in health and diseaseNikolay V Kotov, Declan G Bates, Antonina N Gizatullina, et al.Critical Care (London, England)|June 12, 2026
Computational tools for personalizing treatment of acute respiratory failure, from machine learning to digital twins: a narrative reviewSina Saffaran, Hang Yu, Hossein Shamohammadi, et al.Pageof 8