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Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
October 10, 2024
Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human
Laurent Salphati, Jodie Pang, Emile G Plise, et al.
Toxicology Mechanisms and Methods
|
April 21, 2015
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid
Jacqueline M Tarrant, Preeti Dhawan, Jatinder Singh, et al.
Neoplasia (New York, N.Y.)
|
January 10, 2014
Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models
Thomas O'Brien, Jason Oeh, Yang Xiao, et al.
Cancer Discovery
|
March 24, 2017
Phase I Dose-Escalation Study of Taselisib, an Oral PI3K Inhibitor, in Patients with Advanced Solid Tumors
Dejan Juric, Ian Krop, Ramesh K Ramanathan, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 9, 2012
Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models
Jill M Spoerke, Carol O'Brien, Ling Huw, et al.
Plos One
|
October 7, 2014
Structural basis for resistance to diverse classes of NAMPT inhibitors
Weiru Wang, Kristi Elkins, Angela Oh, et al.
Cell Reports
|
October 4, 2018
The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function
Sairy Hernandez, Jing Qing, Rebecca Hong Thibodeau, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 16, 2014
Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase
Tanja S Zabka, Jatinder Singh, Preeti Dhawan, et al.
Cell Metabolism
|
July 26, 2018
Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State
Anneleen Daemen, Bonnie Liu, Kyung Song, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 1, 2013
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Peter S Dragovich, Kenneth W Bair, Timm Baumeister, et al.
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Search research articles
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Showing results (41-50 of 100) with videos related to
Sort By:
Page
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Xenobiotica; the Fate of Foreign Compounds in Biological Systems
|
October 10, 2024
Preclinical assessment of the PI3Kα selective inhibitor inavolisib and prediction of its pharmacokinetics and efficacious dose in human
Laurent Salphati, Jodie Pang, Emile G Plise, et al.
Toxicology Mechanisms and Methods
|
April 21, 2015
Preclinical models of nicotinamide phosphoribosyltransferase inhibitor-mediated hematotoxicity and mitigation by co-treatment with nicotinic acid
Jacqueline M Tarrant, Preeti Dhawan, Jatinder Singh, et al.
Neoplasia (New York, N.Y.)
|
January 10, 2014
Supplementation of nicotinic acid with NAMPT inhibitors results in loss of in vivo efficacy in NAPRT1-deficient tumor models
Thomas O'Brien, Jason Oeh, Yang Xiao, et al.
Cancer Discovery
|
March 24, 2017
Phase I Dose-Escalation Study of Taselisib, an Oral PI3K Inhibitor, in Patients with Advanced Solid Tumors
Dejan Juric, Ian Krop, Ramesh K Ramanathan, et al.
Clinical Cancer Research : an Official Journal of the American Association for Cancer Research
|
November 9, 2012
Phosphoinositide 3-kinase (PI3K) pathway alterations are associated with histologic subtypes and are predictive of sensitivity to PI3K inhibitors in lung cancer preclinical models
Jill M Spoerke, Carol O'Brien, Ling Huw, et al.
Plos One
|
October 7, 2014
Structural basis for resistance to diverse classes of NAMPT inhibitors
Weiru Wang, Kristi Elkins, Angela Oh, et al.
Cell Reports
|
October 4, 2018
The Kinase Activity of Hematopoietic Progenitor Kinase 1 Is Essential for the Regulation of T Cell Function
Sairy Hernandez, Jing Qing, Rebecca Hong Thibodeau, et al.
Toxicological Sciences : an Official Journal of the Society of Toxicology
|
December 16, 2014
Retinal toxicity, in vivo and in vitro, associated with inhibition of nicotinamide phosphoribosyltransferase
Tanja S Zabka, Jatinder Singh, Preeti Dhawan, et al.
Cell Metabolism
|
July 26, 2018
Pan-Cancer Metabolic Signature Predicts Co-Dependency on Glutaminase and De Novo Glutathione Synthesis Linked to a High-Mesenchymal Cell State
Anneleen Daemen, Bonnie Liu, Kyung Song, et al.
Bioorganic & Medicinal Chemistry Letters
|
August 1, 2013
Identification of 2,3-dihydro-1H-pyrrolo[3,4-c]pyridine-derived ureas as potent inhibitors of human nicotinamide phosphoribosyltransferase (NAMPT)
Peter S Dragovich, Kenneth W Bair, Timm Baumeister, et al.
Page
of 10