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Deepak Sampath

Showing results (81-90 of 100) with videos related to

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Cell|July 30, 2019
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its MobilityJane Guan, Wei Zhou, Marc Hafner, et al.
Bioorganic & Medicinal Chemistry Letters|January 4, 2015
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubilityMark Zak, Bianca M Liederer, Deepak Sampath, et al.
Cancer Discovery|September 21, 2021
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) EfficacyKyung W Song, Kyle A Edgar, Emily J Hanan, et al.
Bioorganic & Medicinal Chemistry Letters|August 23, 2021
Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancerJason R Zbieg, Jun Liang, Jun Li, et al.
Journal of Medicinal Chemistry|January 8, 2016
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)Timothy P Heffron, Robert A Heald, Chudi Ndubaku, et al.
Bioorganic & Medicinal Chemistry Letters|April 2, 2013
Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoformSteven T Staben, Chudi Ndubaku, Nicole Blaquiere, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Discovery of GNE-149 as a Full Antagonist and Efficient Degrader of Estrogen Receptor alpha for ER+ Breast CancerJun Liang, Robert Blake, Jae Chang, et al.
Journal of Medicinal Chemistry|September 1, 2012
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumorsJames F Blake, Rui Xu, Josef R Bencsik, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|March 2, 2018
Conjugation of Indoles to Antibodies through a Novel Self-Immolating LinkerPeter S Dragovich, Robert A Blake, Chunjiao Chen, et al.
Nature Chemical Biology|August 2, 2016
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibitionAaron Boudreau, Hans E Purkey, Anna Hitz, et al.
Pageof 10

Showing results (81-90 of 100) with videos related to

Sort By:
Pageof 10
Cell|July 30, 2019
Therapeutic Ligands Antagonize Estrogen Receptor Function by Impairing Its MobilityJane Guan, Wei Zhou, Marc Hafner, et al.
Bioorganic & Medicinal Chemistry Letters|January 4, 2015
Identification of nicotinamide phosphoribosyltransferase (NAMPT) inhibitors with no evidence of CYP3A4 time-dependent inhibition and improved aqueous solubilityMark Zak, Bianca M Liederer, Deepak Sampath, et al.
Cancer Discovery|September 21, 2021
RTK-Dependent Inducible Degradation of Mutant PI3Kα Drives GDC-0077 (Inavolisib) EfficacyKyung W Song, Kyle A Edgar, Emily J Hanan, et al.
Bioorganic & Medicinal Chemistry Letters|August 23, 2021
Discovery of GNE-502 as an orally bioavailable and potent degrader for estrogen receptor positive breast cancerJason R Zbieg, Jun Liang, Jun Li, et al.
Journal of Medicinal Chemistry|January 8, 2016
The Rational Design of Selective Benzoxazepin Inhibitors of the α-Isoform of Phosphoinositide 3-Kinase Culminating in the Identification of (S)-2-((2-(1-Isopropyl-1H-1,2,4-triazol-5-yl)-5,6-dihydrobenzo[f]imidazo[1,2-d][1,4]oxazepin-9-yl)oxy)propanamide (GDC-0326)Timothy P Heffron, Robert A Heald, Chudi Ndubaku, et al.
Bioorganic & Medicinal Chemistry Letters|April 2, 2013
Discovery of thiazolobenzoxepin PI3-kinase inhibitors that spare the PI3-kinase β isoformSteven T Staben, Chudi Ndubaku, Nicole Blaquiere, et al.
ACS Medicinal Chemistry Letters|June 20, 2020
Discovery of GNE-149 as a Full Antagonist and Efficient Degrader of Estrogen Receptor alpha for ER+ Breast CancerJun Liang, Robert Blake, Jae Chang, et al.
Journal of Medicinal Chemistry|September 1, 2012
Discovery and preclinical pharmacology of a selective ATP-competitive Akt inhibitor (GDC-0068) for the treatment of human tumorsJames F Blake, Rui Xu, Josef R Bencsik, et al.
Chemistry (Weinheim an Der Bergstrasse, Germany)|March 2, 2018
Conjugation of Indoles to Antibodies through a Novel Self-Immolating LinkerPeter S Dragovich, Robert A Blake, Chunjiao Chen, et al.
Nature Chemical Biology|August 2, 2016
Metabolic plasticity underpins innate and acquired resistance to LDHA inhibitionAaron Boudreau, Hans E Purkey, Anna Hitz, et al.
Pageof 10