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Journal of Translational Medicine|May 26, 2011
Combination therapy with vemurafenib (PLX4032/RG7204) and metformin in melanoma cell lines with distinct driver mutationsFranziska Niehr, Erika von Euw, Narsis Attar, et al.Journal of Cell Science|September 1, 2011
Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolismAnna N Cvrljevic, David Akhavan, Min Wu, et al.Cancer Cell|November 12, 2015
Glucose-Mediated N-glycosylation of SCAP Is Essential for SREBP-1 Activation and Tumor GrowthChunming Cheng, Peng Ru, Feng Geng, et al.Proceedings of the National Academy of Sciences of the United States of America|July 24, 2009
The AMPK agonist AICAR inhibits the growth of EGFRvIII-expressing glioblastomas by inhibiting lipogenesisDeliang Guo, Isabel J Hildebrandt, Robert M Prins, et al.Nature Communications|May 31, 2024
The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activityChandra Bhushan Prasad, Adrian Oo, Yujie Liu, et al.Neuro-Oncology|May 8, 2019
Oncolytic HSV therapy increases trametinib access to brain tumors and sensitizes them in vivoJi Young Yoo, Jessica Swanner, Yoshihiro Otani, et al.Science Advances|April 18, 2025
Targeting PGM3 abolishes SREBP-1 activation-hexosamine synthesis feedback regulation to effectively suppress brain tumor growthHuali Su, Yaogang Zhong, Liqing He, et al.Clinical Cancer Research : an Official Journal of the American Association for Cancer Research|June 10, 2016
Inhibition of SOAT1 Suppresses Glioblastoma Growth via Blocking SREBP-1-Mediated LipogenesisFeng Geng, Xiang Cheng, Xiaoning Wu, et al.Cell Reports. Medicine|September 5, 2024
Combinatorial targeting of glutamine metabolism and lysosomal-based lipid metabolism effectively suppresses glioblastomaYaogang Zhong, Feng Geng, Logan Mazik, et al.Science Translational Medicine|January 28, 2026
SREBP-1 increases glucose uptake to promote tumor resistance to lysosome inhibitionYaogang Zhong, Feng Geng, Huali Su, et al.Pageof 7