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Bioorganic & Medicinal Chemistry Letters|September 11, 2012
HCV NS5A replication complex inhibitors. Part 2: investigation of stilbene prolinamidesDenis R St Laurent, Makonen Belema, Min Gao, et al.Journal of Medicinal Chemistry|January 21, 2014
Hepatitis C virus NS5A replication complex inhibitors. Part 6: Discovery of a novel and highly potent biarylimidazole chemotype with inhibitory activity toward genotypes 1a and 1b repliconsMakonen Belema, Van N Nguyen, Jeffrey L Romine, et al.Bioorganic & Medicinal Chemistry Letters|January 1, 2013
HCV NS5A replication complex inhibitors. Part 3: discovery of potent analogs with distinct core topologiesOmar D Lopez, Van N Nguyen, Denis R St Laurent, et al.Journal of Medicinal Chemistry|March 19, 2004
Design and synthesis of a fluoroindolocarbazole series as selective topoisomerase I active agents. Discovery of water-soluble 3,9-difluoro-12,13-dihydro-13-[6-amino-beta-D-glucopyranosyl]-5H,13H-benzo[b]- thienyl[2,3-a]pyrrolo[3,4-c]carbazole- 5,7(6H)-dione (BMS-251873) with curative antitumor activity against prostate carcinoma xenograft tumor modelBalu N Balasubramanian, Denis R St Laurent, Mark G Saulnier, et al.Journal of Medicinal Chemistry|April 12, 2013
HCV NS5A replication complex inhibitors. Part 4. Optimization for genotype 1a replicon inhibitory activityDenis R St Laurent, Michael H Serrano-Wu, Makonen Belema, et al.Journal of Medicinal Chemistry|April 2, 2005
Discovery of a fluoroindolo[2,3-a]carbazole clinical candidate with broad spectrum antitumor activity in preclinical tumor models superior to the marketed oncology drug, CPT-11Mark G Saulnier, Balu N Balasubramanian, Byron H Long, et al.The Journal of Organic Chemistry|September 7, 2017
Development of the Large-Scale Synthesis of Tetrahydropyran Glycine, a Precursor to the HCV NS5A Inhibitor BMS-986097Arvind Mathur, Bei Wang, Daniel Smith, et al.Journal of Medicinal Chemistry|February 14, 2014
Hepatitis C virus NS5A replication complex inhibitors: the discovery of daclatasvirMakonen Belema, Van N Nguyen, Carol Bachand, et al.Pageof 2