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Endocrinology|March 7, 2026
A simple and robust reporter-based framework for deep functional characterization of PPARγ mutantsRosalie Baak, Denise Westland, Eline de Lange, et al.
Urologic Oncology|October 28, 2025
Molecular subtyping of advanced bladder cancer patients and patient-derived organoids based on a 3-marker immunohistochemistry approach to evaluate chemotherapy sensitivityBastiaan J Viergever, Alba C Zuidema, Trudy Jonges, et al.
Scientific Reports|June 17, 2022
Recurrent exon-deleting activating mutations in AHR act as drivers of urinary tract cancerJudith M Vlaar, Anouska Borgman, Eric Kalkhoven, et al.
Metabolites|May 24, 2024
Direct Infusion Mass Spectrometry to Rapidly Map Metabolic Flux of Substrates Labeled with Stable IsotopesNils W F Meijer, Susan Zwakenberg, Johan Gerrits, et al.
Human Genetics|September 21, 2019
MDH1 deficiency is a metabolic disorder of the malate-aspartate shuttle associated with early onset severe encephalopathyMelissa H Broeks, Hanan E Shamseldin, Amal Alhashem, et al.
Molecular & Cellular Proteomics : MCP|July 21, 2022
Phosphoproteomic Analysis of FLCN Inactivation Highlights Differential Kinase Pathways and Regulatory TFEB PhosphoserinesIris E Glykofridis, Alex A Henneman, Jesper A Balk, et al.
Cell Reports|August 30, 2023
The malate-aspartate shuttle is important for de novo serine biosynthesisMelissa H Broeks, Nils W F Meijer, Denise Westland, et al.
Molecular Cell|November 1, 2024
mTORC1 restricts TFE3 activity by auto-regulating its presence on lysosomesSusan Zwakenberg, Denise Westland, Robert M van Es, et al.
Elife|January 18, 2021
Loss of FLCN-FNIP1/2 induces a non-canonical interferon response in human renal tubular epithelial cellsIris E Glykofridis, Jaco C Knol, Jesper A Balk, et al.
Nature Communications|November 19, 2022
PPARγ lipodystrophy mutants reveal intermolecular interactions required for enhancer activationMaria Stahl Madsen, Marjoleine F Broekema, Martin Rønn Madsen, et al.
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