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Science (New York, N.Y.)|March 24, 2022
A structural basis for amylin receptor phenotypeJianjun Cao, Matthew J Belousoff, Yi-Lynn Liang, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 24, 2012
Glucagon-like peptide-1 receptor dimerization differentially regulates agonist signaling but does not affect small molecule allosteryKaleeckal G Harikumar, Denise Wootten, Delia I Pinon, et al.
Frontiers in Endocrinology|December 24, 2021
Discovery of a Positive Allosteric Modulator of Cholecystokinin Action at CCK1R in Normal and Elevated CholesterolKaleeckal G Harikumar, Thomas Coudrat, Aditya J Desai, et al.
ACS Pharmacology & Translational Science|March 29, 2020
Dominant Negative G Proteins Enhance Formation and Purification of Agonist-GPCR-G Protein Complexes for Structure DeterminationYi-Lynn Liang, Peishen Zhao, Christopher Draper-Joyce, et al.
Biochemistry|February 20, 2024
Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3Isabella C Russell, Xin Zhang, Fabian Bumbak, et al.
Molecular Pharmacology|December 25, 2015
A Hydrogen-Bonded Polar Network in the Core of the Glucagon-Like Peptide-1 Receptor Is a Fulcrum for Biased Agonism: Lessons from Class B Crystal StructuresDenise Wootten, Christopher A Reynolds, Cassandra Koole, et al.
The Journal of Biological Chemistry|May 3, 2018
Two distinct domains of the glucagon-like peptide-1 receptor control peptide-mediated biased agonismSaifei Lei, Lachlan Clydesdale, Antao Dai, et al.
Nature Communications|November 17, 2022
Understanding VPAC receptor family peptide binding and selectivitySarah J Piper, Giuseppe Deganutti, Jessica Lu, et al.
Molecular Pharmacology|August 30, 2012
Small molecule allosteric modulation of the glucagon-like Peptide-1 receptor enhances the insulinotropic effect of oxyntomodulinFrancis S Willard, Denise Wootten, Aaron D Showalter, et al.
Biochemical Pharmacology|February 19, 2018
Extracellular loops 2 and 3 of the calcitonin receptor selectively modify agonist binding and efficacyEmma Dal Maso, Yue Zhu, Vi Pham, et al.
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