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Plos Computational Biology|February 10, 2022
Chiral evasion and stereospecific antifolate resistance in Staphylococcus aureusSiyu Wang, Stephanie M Reeve, Graham T Holt, et al.
Bioorganic & Medicinal Chemistry Letters|August 31, 2010
Natural product derivatives with bactericidal activity against Gram-positive pathogens including methicillin-resistant Staphylococcus aureus and vancomycin-resistant Enterococcus faecalisJoshua B Phillips, Adrienne E Smith, Brian R Kusche, et al.
Cell Chemical Biology|December 13, 2016
MRSA Isolates from United States Hospitals Carry dfrG and dfrK Resistance Genes and Succumb to Propargyl-Linked AntifolatesStephanie M Reeve, Eric W Scocchera, Narendran G-Dayanadan, et al.
ACS Medicinal Chemistry Letters|July 21, 2016
Charged Nonclassical Antifolates with Activity Against Gram-Positive and Gram-Negative PathogensEric Scocchera, Stephanie M Reeve, Santosh Keshipeddy, et al.
Journal of Medicinal Chemistry|November 15, 2008
Synthetic and crystallographic studies of a new inhibitor series targeting Bacillus anthracis dihydrofolate reductaseJennifer M Beierlein, Kathleen M Frey, David B Bolstad, et al.
Plos One|February 21, 2012
Toward new therapeutics for skin and soft tissue infections: propargyl-linked antifolates are potent inhibitors of MRSA and Streptococcus pyogenesKishore Viswanathan, Kathleen M Frey, Eric W Scocchera, et al.
Molecular Carcinogenesis|October 12, 2013
Development of intestinal organoids as tissue surrogates: cell composition and the epigenetic control of differentiationLi Cao, Anton Kuratnik, Wanli Xu, et al.
Leukemia Research|January 7, 2019
Tropolone-induced effects on the unfolded protein response pathway and apoptosis in multiple myeloma cells are dependent on ironStaci L Haney, Michelle L Varney, Hannah R Safranek, et al.
Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences|April 10, 2025
Comparative pharmacokinetics of seven propargyl-linked antifolate antibiotics in the mouseJohn Hoody, Jeremy B Alverson, Santosh Keshipeddy, et al.
Biochemical Pharmacology|November 11, 2024
Evaluation of UCP1162, a potent propargyl-linked inhibitor of dihydrofolate reductase with potential application to cancer and autoimmune diseaseDidem Ozcan Tezgin, Shan Kurkcu, Debjani Si, et al.
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