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Neurobiology of Disease|March 17, 2011
GPA protects the nigrostriatal dopamine system by enhancing mitochondrial functionTamas L Horvath, Derek M Erion, John D Elsworth, et al.
The Journal of Pharmacology and Experimental Therapeutics|September 18, 2021
Selective Acetyl-CoA Carboxylase 1 Inhibitor Improves Hepatic Steatosis and Hepatic Fibrosis in a Preclinical Nonalcoholic Steatohepatitis ModelYumiko Okano Tamura, Jun Sugama, Shinji Iwasaki, et al.
Plos One|January 29, 2020
Acetyl-CoA carboxylase 1 and 2 inhibition ameliorates steatosis and hepatic fibrosis in a MC4R knockout murine model of nonalcoholic steatohepatitisMitsuharu Matsumoto, Hiroaki Yashiro, Hitomi Ogino, et al.
Drug Metabolism and Disposition: the Biological Fate of Chemicals|July 16, 2016
Determination of Unbound Partition Coefficient and in Vitro-in Vivo Extrapolation for SLC13A Transporter-Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A Brown, et al.
The Journal of Biological Chemistry|December 9, 2015
Characterization of a Novel Intestinal Glycerol-3-phosphate Acyltransferase Pathway and Its Role in Lipid HomeostasisIrani Khatun, Ronald W Clark, Nicholas B Vera, et al.
Journal of Mass Spectrometry : JMS|March 30, 2018
Differential mobility spectrometry (DMS) reveals the elevation of urinary acetylcarnitine in non-human primates (NHPs) exposed to radiationNicholas B Vera, Zhidan Chen, Evan Pannkuk, et al.
ACS Chemical Biology|March 11, 2022
Genome-wide CRISPR Screening to Identify Drivers of TGF-β-Induced Liver Fibrosis in Human Hepatic Stellate CellsShan Yu, Matthew Ericson, Andrea Fanjul, et al.
Diabetes|March 6, 2014
Abrogating monoacylglycerol acyltransferase activity in liver improves glucose tolerance and hepatic insulin signaling in obese miceAngela M Hall, Nisreen Soufi, Kari T Chambers, et al.
Scientific Reports|July 9, 2015
FGF21 does not require interscapular brown adipose tissue and improves liver metabolic profile in animal models of obesity and insulin-resistanceBarbara Bernardo, Min Lu, Gautam Bandyopadhyay, et al.
Molecular Metabolism|June 6, 2017
FGF21 does not require adipocyte AMP-activated protein kinase (AMPK) or the phosphorylation of acetyl-CoA carboxylase (ACC) to mediate improvements in whole-body glucose homeostasisEmilio P Mottillo, Eric M Desjardins, Andreas M Fritzen, et al.
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