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Nature Chemical Biology|September 21, 2023
Continuous directed evolution of a compact CjCas9 variant with broad PAM compatibilityLukas Schmidheini, Nicolas Mathis, Kim Fabiano Marquart, et al.
Science Translational Medicine|March 16, 2022
In vivo prime editing of a metabolic liver disease in miceDesirée Böck, Tanja Rothgangl, Lukas Villiger, et al.
Science Translational Medicine|May 13, 2026
Prime editing of a pathogenic <i>Scn1a</i> allele ameliorates seizure phenotypes in a GEFS<sup>+</sup> mouse modelLucas Kissling, Francesca Pietrafesa, Matteo Ranucci, et al.
Nature Biotechnology|June 21, 2024
Machine learning prediction of prime editing efficiency across diverse chromatin contextsNicolas Mathis, Ahmed Allam, András Tálas, et al.
Molecular Therapy : the Journal of the American Society of Gene Therapy|March 8, 2024
In vivo base editing of a pathogenic Eif2b5 variant improves vanishing white matter phenotypes in miceDesirée Böck, Ilma M Revers, Anastasia S J Bomhof, et al.
Nature Communications|March 7, 2024
Enhancing prime editor activity by directed protein evolution in yeastYanik Weber, Desirée Böck, Anastasia Ivașcu, et al.
Plos Pathogens|May 5, 2020
Salmonella Typhimurium discreet-invasion of the murine gut absorptive epitheliumStefan A Fattinger, Desirée Böck, Maria Letizia Di Martino, et al.
NPJ Parkinson'S Disease|October 22, 2024
Direct and indirect regulation of β-glucocerebrosidase by the transcription factors USF2 and ONECUT2Kathi Ging, Lukas Frick, Johannes Schlachetzki, et al.
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