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Mechanisms of Ageing and Development|June 24, 2026
HTZ-1/H2A.Z expression sustains transcriptional programs that regulate Caenorhabditis elegans lifespanBeijia Xie, Enzo Scifo, Ioanna-Maria Menegatou, et al.Molecular Cell|June 27, 2025
Interaction with AK2A links AIFM1 to cellular energy metabolismRobin Alexander Rothemann, Egor Pavlenko, Mrityunjoy Mondal, et al.Nature Neuroscience|November 11, 2014
Mechanism and treatment for learning and memory deficits in mouse models of Noonan syndromeYong-Seok Lee, Dan Ehninger, Miou Zhou, et al.EMBO Reports|March 17, 2022
CEST-2.2 overexpression alters lipid metabolism and extends longevity of mitochondrial mutantsAntonia Piazzesi, Yiru Wang, Joshua Jackson, et al.Science Advances|April 11, 2025
Loss of Ten1 in mice induces telomere shortening and models human dyskeratosis congenitaAdrián Sanz-Moreno, Lore Becker, Kan Xie, et al.Proceedings of the National Academy of Sciences of the United States of America|February 23, 2018
Epigenetic alterations in longevity regulators, reduced life span, and exacerbated aging-related pathology in old father offspring miceKan Xie, Devon P Ryan, Brandon L Pearson, et al.Nature Communications|August 2, 2017
Every-other-day feeding extends lifespan but fails to delay many symptoms of aging in miceKan Xie, Frauke Neff, Astrid Markert, et al.The Journal of Clinical Investigation|July 19, 2013
Rapamycin extends murine lifespan but has limited effects on agingFrauke Neff, Diana Flores-Dominguez, Devon P Ryan, et al.Nature Communications|November 12, 2022
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J miceKan Xie, Helmut Fuchs, Enzo Scifo, et al.Pageof 9