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Journal of Pharmacokinetics and Pharmacodynamics|November 16, 2012
Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotinDhaval K Shah, Nahor Haddish-Berhane, Alison Betts
Journal of Clinical Pharmacology|November 14, 2024
Meta-Analysis of Exposure-Adverse Event Relationships for Antibody-Drug ConjugatesCheng Wang, Linda Irons, Holly Kimko, et al.
The AAPS Journal|August 16, 2017
Development of a Translational Physiologically Based Pharmacokinetic Model for Antibody-Drug Conjugates: a Case Study with T-DM1Antari Khot, Jay Tibbitts, Dan Rock, et al.
Pharmaceutical Research|February 11, 2015
Application of Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Antibody-Drug Conjugate DevelopmentAman P Singh, Young G Shin, Dhaval K Shah
The AAPS Journal|February 10, 2019
Estimation of Solid Tumor Doubling Times from Progression-Free Survival Plots Using a Novel Statistical ApproachKatherine Kay, Keith Dolcy, Robert Bies, et al.
CPT: Pharmacometrics & Systems Pharmacology|November 28, 2018
Target-Mediated Drug Disposition Model for Bispecific Antibodies: Properties, Approximation, and Optimal Dosing StrategyJohannes Schropp, Antari Khot, Dhaval K Shah, et al.
Journal of Pharmaceutical Sciences|December 5, 2022
Pharmacokinetic Evaluation of Thermosensitive Sustained Release Formulations Developed for Subcutaneous Delivery of Protein TherapeuticsPooja M Rajadhyaksha, Divyesh H Shastri, Dhaval K Shah
Journal of Pharmacokinetics and Pharmacodynamics|January 28, 2022
Physiologically-based pharmacokinetic model for 2,4-dinitrophenolLyndsey F Meyer, Pooja M Rajadhyaksha, Dhaval K Shah
Journal of Clinical Medicine|April 3, 2021
Whole-Body Pharmacokinetics and Physiologically Based Pharmacokinetic Model for Monomethyl Auristatin E (MMAE)Hsuan Ping Chang, Yuen Kiu Cheung, Dhaval K Shah
Drug Metabolism and Disposition: the Biological Fate of Chemicals|February 23, 2020
Evaluation of Quantitative Relationship Between Target Expression and Antibody-Drug Conjugate Exposure Inside Cancer CellsSharad Sharma, Zhe Li, David Bussing, et al.
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