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Nature|November 22, 2005
A phosphatase complex that dephosphorylates gammaH2AX regulates DNA damage checkpoint recoveryMichael-Christopher Keogh, Jung-Ae Kim, Michael Downey, et al.
Molecular Cell|October 28, 2008
Atomic structure of the KEOPS complex: an ancient protein kinase-containing molecular machineDaniel Y L Mao, Dante Neculai, Michael Downey, et al.
ACS Medicinal Chemistry Letters|February 18, 2026
Design of a Targeted Covalent Probe to Interrogate the DNA Polymerase Activity of PolθMonica Bubenik, Pavel Mader, Stephen Orlicky, et al.
Proceedings of the National Academy of Sciences of the United States of America|October 22, 2008
Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotesScott J Dixon, Yaroslav Fedyshyn, Judice L Y Koh, et al.
Molecular Cell|February 14, 2012
OTUB1 co-opts Lys48-linked ubiquitin recognition to suppress E2 enzyme functionYu-Chi Juang, Marie-Claude Landry, Mario Sanches, et al.
Molecular Cell|January 18, 2016
HELB Is a Feedback Inhibitor of DNA End ResectionJán Tkáč, Guotai Xu, Hemanta Adhikary, et al.
Molecular Systems Biology|May 30, 2018
Mapping DNA damage-dependent genetic interactions in yeast via party mating and barcode fusion geneticsJ Javier Díaz-Mejía, Albi Celaj, Joseph C Mellor, et al.
Nature Chemical Biology|April 9, 2026
The molecular glue CLEO4-88 inhibits the ACAA1 thiolase by induced binding to GID4Chetan K Chana, Ines Ben Makhlouf, Jaeyoun Kim, et al.
Science Translational Medicine|January 29, 2011
Uroporphyrinogen decarboxylase is a radiosensitizing target for head and neck cancerEmma Ito, Shijun Yue, Eduardo H Moriyama, et al.
Cell|February 11, 2009
The RIDDLE syndrome protein mediates a ubiquitin-dependent signaling cascade at sites of DNA damageGrant S Stewart, Stephanie Panier, Kelly Townsend, et al.
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